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    The pilus usher controls protein interactions via domain masking and is functional as an oligomer

    Biochemical analyses show that in the Escherichia coli type I pilus the plug domain controls activation of usher by masking the substrate-binding site in the C-terminal domains when usher is in resting state.

    Glenn T Werneburg, Nadine S Henderson… in Nature Structural & Molecular Biology (2015)