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Article
Machine Learning and Artificial Intelligence to Improve Interpretation of Urodynamics
We sought to review and discuss the current state and future trajectory of machine learning in interpretation of urodynamics studies. We sought to identify the most promising opportunities for improvement in u...
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Article
Open AccessMicrobe-metabolite interaction networks, antibiotic resistance, and in vitro reconstitution of the penile prosthesis biofilm support a paradigm shift from infection to colonization
To understand differences between asymptomatic colonized and infected states of indwelling medical devices, we sought to determine penile prosthesis biofilm composition, microbe-metabolite interaction networks...
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Article
Neural networks outperform expert humans in predicting patient impressions of symptomatic improvement following overactive bladder treatment
The objective was to accurately predict patient-centered subjective outcomes following the overactive bladder (OAB) treatments OnabotulinumtoxinA (OBTX-A) injection and sacral neuromodulation (SNM) using a neu...
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Reference Work Entry In depth
Patient-Reported Outcome Measures in Neurogenic Lower Urinary Tract Dysfunction
Patient-reported outcome measures, generally in the form of questionnaires, are arguably the most reliable assessment of patient quality of life. They convey a personal account of the patient without any outsi...
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Reference Work Entry In depth
International Guidelines of Neurogenic Lower Urinary Tract Dysfunction
Guidelines regarding neurogenic lower urinary tract dysfunction have been put forth by urologic associations and other clinical advisory systems throughout the world. The major European, American, and internat...
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Living Reference Work Entry In depth
International Guidelines of Neurogenic Lower Urinary Tract Dysfunction
Guidelines regarding neurogenic lower urinary tract dysfunction have been put forth by urologic associations and other clinical advisory systems throughout the world. The major European, American, and internat...
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Article
Pelvic Organ Prolapse in Patients with Congenital Genitourinary Conditions
We discuss the etiology of pelvic organ prolapse in women with congenital conditions, the features and considerations that distinguish it from that of the general population, and the treatment strategies. We a...
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Living Reference Work Entry In depth
Patient-Reported Outcome Measures in Neurogenic Lower Urinary Tract Dysfunction
Patient-reported outcome measures, generally in the form of questionnaires, are arguably the most reliable assessment of patient quality of life. They convey a personal account of the patient without any outsi...
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Article
Open AccessProcessive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis
Uropathogenic Escherichia coli assemble surface structures termed pili or fimbriae to initiate infection of the urinary tract. P pili facilitate bacterial colonization of the kidney and pyelonephritis. P pili are...
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Article
Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD
Pathogenic bacteria such as Escherichia coli assemble surface structures termed pili, or fimbriae, to mediate binding to host-cell receptors1. Type 1 pili are assembled via the conserved chaperone–usher pathway2–
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Article
Patient-reported quality of life progression in men with prostate cancer following primary cryotherapy, cyberknife, or active holistic surveillance
Technological advancements have led to the success of minimally invasive treatment modalities for prostate cancer such as CyberKnife and Cryotherapy. Here, we investigate patient-reported urinary function, bow...
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Article
PSA kinetics following primary focal cryotherapy (hemiablation) in organ-confined prostate cancer patients
We aim to evaluate prostate-specific antigen (PSA) trends in post-primary focal cryotherapy (PFC) patients.
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Article
The pilus usher controls protein interactions via domain masking and is functional as an oligomer
Biochemical analyses show that in the Escherichia coli type I pilus the plug domain controls activation of usher by masking the substrate-binding site in the C-terminal domains when usher is in resting state.
