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Article
Impacts of age, type 2 diabetes, and hypertension on circulating neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 after prolonged work in the heat in men
Prolonged work in the heat increases the risk of acute kidney injury (AKI) in young men. Whether aging and age-associated chronic disease may exacerbate the risk of AKI remains unclear.
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Article
Open AccessBeach day or deadly heatwave? Content analysis of media images from the 2021 Heat Dome in Canada
During extreme heat events (EHEs) the public often learns about health protective actions through the media. Visual news coverage can act as a powerful tool to help convey complex health protective actions to ...
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Article
Changes in surrogate markers of intestinal epithelial injury and microbial translocation in young and older men during prolonged occupational heat stress in temperate and hot conditions
Exertional heat stress can cause damage to the intestinal epithelium and disrupt gastrointestinal barrier integrity, leading to microbial translocation (MT) linked to the development of heat stroke. This study...
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Article
GH and IGF-1 in skin interstitial fluid and blood are associated with heat loss responses in exercising young adults
Sweat glands and cutaneous vessels possess growth hormone (GH) and insulin-like growth factor 1 (IGF-1) receptors. Here, we assessed if exercise increases GH and IGF-1 in skin interstitial fluid, and whether b...
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Article
Recommended water immersion duration for the field treatment of exertional heat stroke when rectal temperature is unavailable
The recommended treatment for exertional heat stroke is immediate, whole-body immersion in < 10 °C water until rectal temperature (Tre) reaches ≤ 38.6 °C. However, real-time Tre assessment is not always feasible ...
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Article
Serum klotho concentrations in older men with hypertension or type 2 diabetes during prolonged exercise in temperate and hot conditions
Klotho is a cytoprotective protein that increases during acute physiological stressors (e.g., exercise heat stress), although age-related declines in klotho may underlie cellular vulnerability to heat stress. ...
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Article
Effects of ingestion of isomaltulose beverage on plasma volume and thermoregulatory responses during exercise in the heat
Isomaltulose is a low glycemic and insulinaemic carbohydrate increasingly used as an alternative sweetener in commercial beverages. While isomaltulose beverages can improve hydration status compared to sucrose...
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Article
Interindividual Differences in Trainability and Moderators of Cardiorespiratory Fitness, Waist Circumference, and Body Mass Responses: A Large-Scale Individual Participant Data Meta-analysis
Although many studies have assumed variability reflects variance caused by exercise training, few studies have examined whether interindividual differences in trainability are present following exercise traini...
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Article
The impact of age, type 2 diabetes and hypertension on heart rate variability during rest and exercise at increasing levels of heat stress
In older adults with type 2 diabetes (T2D) and hypertension (HTN), cardiac autonomic modulation is markedly attenuated during exercise-heat stress. However, the extent to which this impairment is evident under...
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Article
Comparisons of isomaltulose, sucrose, and mixture of glucose and fructose ingestions on postexercise hydration state in young men
Isomaltulose is a low glycemic and insulinaemic carbohydrate available as a constituent in sports drink. However, it remains unclear whether postexercise rehydration achieved by isomaltulose drink ingestion al...
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Article
Impact of uncomplicated controlled hypertension on thermoregulation during exercise-heat stress
Exercise is promoted for management of hypertension and as a general healthy behavior, but environmental conditions are seldom considered in these recommendations. Hypertension may affect skin blood flow and s...
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Article
Exploring Differences in Cardiorespiratory Fitness Response Rates Across Varying Doses of Exercise Training: A Retrospective Analysis of Eight Randomized Controlled Trials
This study tested the hypothesis that greater mean changes in cardiorespiratory fitness (CRF), in either the absence or presence of reduced interindividual variability, explain larger CRF response rates follow...
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Article
Exercise-heat tolerance in middle-aged-to-older men with type 2 diabetes
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Article
Whole-body heat exchange in women during constant- and variable-intensity work in the heat
Time-weighted averaging is used in occupational heat stress guidelines to estimate the metabolic demands of variable-intensity work. However, compared to constant-intensity work of the same time-weighted avera...
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Article
Cardiac autonomic modulation in type 1 diabetes during exercise-heat stress
Cardiac autonomic modulation, as assessed by heart rate variability (HRV), is independently attenuated by both type 1 diabetes (T1D) and exercise-heat stress, although their combined effects remain unclear. We...
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Article
Diminished heart rate variability in type 2 diabetes is exacerbated during exercise-heat stress
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Article
Does α1-adrenergic receptor blockade modulate sweating during incremental exercise in young endurance-trained men?
Human eccrine sweat glands respond to α1-adrenergic receptor agonists. We recently reported that adrenergic mechanisms contribute to sweating in endurance-trained men during an incremental exercise to volitional ...
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Article
Age differences in cardiac autonomic regulation during intermittent exercise in the heat
This study aimed to detect potential differences in heart-rate variability (HRV) during a moderate-intensity intermittent exercise in the heat among physically active young (25.8 ± 1.9 years), middle-aged (43....
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Chapter
Climate Change and Heat Exposure: Impact on Health in Occupational and General Populations
The projected rise in the frequency and intensity of extreme heat conditions associated with global climate change represent the greatest threat to human health of the twenty-first century. This threat is part...
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Article
Impaired whole-body heat loss in type 1 diabetes during exercise in the heat: a cause for concern?
