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    Reference Work Entry In depth

    Calcitonin

    Girish V. Shah in Encyclopedia of Cancer (2017)

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    Living Reference Work Entry In depth

    Calcitonin

    Girish V. Shah in Encyclopedia of Cancer

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    Protocol

    Methods for Evaluation of Structural and Biological Properties of Antiinvasive Natural Products

    Prostate cancer is considered the most common cancer form among males in Western countries. Very limited options are available for the treatment of advanced metastatic prostate cancer. More than 50% of today’s...

    Mudit Mudit, Mohammad Khanfar, Girish V. Shah in Drug Design and Discovery (2011)

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    Reference Work Entry In depth

    Calcitonin

    Girish V. Shah in Encyclopedia of Cancer (2009)

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    Article

    Calcitonin receptor-stimulated migration of prostate cancer cells is mediated by urokinase receptor-integrin signaling

    Abundance of calcitonin (CT) and calcitonin receptor (CTR) mRNA in primary prostate tumors positively correlates with tumor grade, and exogenously added CT increases the invasion of prostate cancer cell lines....

    Shibu Thomas, Maurizio Chiriva-Internati in Clinical & Experimental Metastasis (2007)

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    Article

    A synthetic peptide derived from mouse pituitary calcitonin cDNA sequence exhibits potent inhibition of prolactin secretion and prolactin mRNA abundance in primary mouse pituitary cells

    We have shown that gonadotrophs synthesize and secrete immunoreactive calcitonin (CT)-like peptide, and CT is a potent inhibitor of prolactin (PRL) secretion and gene transcription. CT cDNA cloned from LßT2 ce...

    Trupti Kulkarni-Paranjape, Girish V. Shah in Endocrine (2007)

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    Article

    Calcitonin inhibits prolactin promoter activity in rat pituitary GGH3 cells

    Previous findings from our laboratory have shown that pituitary calcitonin-like peptide (pit-CT) is synthesized and released by gonadotrophs and inhibits prolactin (PRL) release, synthesis, and lactotroph prol...

    Yuan Ren, Ya-** Sun, Girish V. Shah in Endocrine (2003)

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    Article

    Calcitonin-like peptide containing gonadotrophs are juxtaposed to cup-shaped lactotrophs

    Calcitonin (CT) is known to inhibit basal and TRH-stimulated prolactin release in cultured anterior pituitary cells in vitro and pituitary CT-like peptide (pit-CT) is synthesized and released by isolated anter...

    Bibie M. Chronwall, Scott A. Sands, Zhuang Li, Girish V. Shah in Endocrine (1996)

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    Article

    Estrogen attenuates expression of calcitonin-like immunoreactivity in the anterior pituitary gland

    Estrogens increase prolactin (PRL) synthesis and release in rats and humans, whereas pituitary-derived calcitonin-like immunoreactive peptide (pit-CT) inhibits PRL gene expression and release. To test the hypo...

    Zhuang Li, Girish V. Shah in Endocrine (1995)

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    Article

    Calcitonin inhibits prolactin gene transcription in rat pituitary cells

    Our recent studies have shown that calcitonin (CT)-like immunoreactive peptide is synthesized and released from cultured rat anterior pituitary (AP) cells, and may serve as a paracrine inhibitor of PRL release...

    Qing Xue-Zhang, Scott M. Stanley, Girish V. Shah in Endocrine (1995)