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Protocol
VarGibbs Usage in the Optimization of Nearest-Neighbor Parameters and Prediction of Melting Temperature of RNA Duplexes
The nearest-neighbor (NN) model is a general tool for the evaluation for oligonucleotide thermodynamic stability. It is primarily used for the prediction of melting temperatures but has also found use in RNA s...
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Chapter and Conference Paper
Mesoscopic Evaluation of DNA Mismatches in PCR Primer-Target Hybridisation to Detect SARS-CoV-2 Variants of Concern
Mismatches are any type of base-pairs other than AT and CG. They are an expected occurrence in PCR primer-target hybridisation and may interfere with the amplification and in some cases even prevent the detect...
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Article
Open AccessOptical and theoretical study of strand recognition by nucleic acid probes
Detection of nucleic acids is crucial to the study of their basic properties and consequently to applying this knowledge to the determination of pathologies such as cancer. In this work, our goal is to determi...
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Article
A memory-optimal many-to-many semi-stream join
Semi-stream join algorithms join a fast stream input with a disk-based master data relation. A common class of these algorithms is derived from hash joins: they use the stream as build input for a main hash ta...
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Chapter and Conference Paper
A Multi-way Semi-stream Join for a Near-Real-Time Data Warehouse
Semi-stream processing, the operation of joining a stream of data with non-stream disk-based master data, is a crucial component of near real-time data warehousing. The requirements for semi-stream joins are f...
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Chapter and Conference Paper
Automatic Generation of User Interface Layouts for Alternative Screen Orientations
Creating multiple layout alternatives for graphical user interfaces to accommodate different screen orientations for mobile devices is labor intensive. Here, we investigate how such layout alternatives can be ...
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Chapter and Conference Paper
Optimising Queue-Based Semi-stream Joins by Introducing a Queue of Frequent Pages
Semi-stream joins perform a join between a stream and a disk-based table. These joins can easily deal with typical workloads in online real-time data warehousing in many scenarios and with relatively modest sy...
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Chapter and Conference Paper
Eyes and Keys: An Evaluation of Click Alternatives Combining Gaze and Keyboard
With eye gaze tracking technology entering the consumer market, there is an increased interest in using it as an input device, similar to the mouse. This holds promise for situations where a typical desk space...
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Article
Efficient processing of streaming updates with archived master data in near-real-time data warehousing
In order to make timely and effective decisions, businesses need the latest information from data warehouse repositories. To keep these repositories up-to-date with respect to end user updates, near-real-time ...
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Chapter and Conference Paper
Optimizing Queue-Based Semi-Stream Joins with Indexed Master Data
In Data Stream Management Systems (DSMS) semi-stream processing has become a popular area of research due to the high demand of applications for up-to-date information (e.g. in real-time data warehousing). A c...
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Chapter and Conference Paper
SSCJ: A Semi-Stream Cache Join Using a Front-Stage Cache Module
Semi-stream processing has become an emerging area of research in the field of data stream management. One common operation in semi-stream processing is joining a stream with disk-based master data using a joi...
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Chapter and Conference Paper
An Evaluation of Stacking and Tiling Features within the Traditional Desktop Metaphor
Having many open windows on the desktop can lead to various usability problems. Window content may get occluded by other windows and working with multiple windows may get cumbersome. In this paper, we evaluate...
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Chapter and Conference Paper
Evaluating Direct Manipulation Operations for Constraint-Based Layout
Layout managers are used to control the placement of widgets in graphical user interfaces (GUIs). Constraint-based layout managers are more powerful than other ones. However, they are also more complex and the...
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Chapter and Conference Paper
Eyes Only: Navigating Hypertext with Gaze
Eye gaze tracking is an obvious candidate for a future input device, perhaps even for everyday computing. The hard problems with gaze-controlled interfaces are inaccuracy and inadvertent clicking. We attempt t...
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Article
Influence of operating conditions on the performance of biomass-based Fischer–Tropsch synthesis
The environmental concerns and the European liquid (bio) fuel regulations have determined a growing demand on biofuels. Fischer–Tropsch synthesis can provide clean synthetic fuels containing low concentrations...
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Chapter and Conference Paper
Efficient Usage of Memory Resources in Near-Real-Time Data Warehousing
In the context of near-real-time data warehousing the user’s updates generated at data source level need to be stored into warehouse as soon as they occur. Before loading these updates into the warehouse they ...
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Chapter and Conference Paper
A Parametric Analysis of Stream Based Joins
Online stream processing is an emerging research area in the field of computer science. Common examples where online stream processing is important are network traffic monitoring, web log analysis and real-tim...
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Chapter and Conference Paper
A Lightweight Stream-Based Join with Limited Resource Consumption
Many stream-based applications have plenty of resources available to them, but there are also applications where resource consumption must be limited. For one important class of stream-based joins, where a str...
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Chapter and Conference Paper
Form-and-Fact Based Modeling
A conceptual data model for an information system specifies the fact structures of interest as well as the constraints and derivation rules that apply to the business domain being modeled. Fact-based modeling ...
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Article
Open AccessOrigin of multiple periodicities in the Fourier power spectra of the Plasmodium falciparum genome
Fourier transforms and their associated power spectra are used for detecting periodicities and protein-coding genes and is generally regarded as a well established technique. Many of the periodicities which ha...
