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    Chapter

    Plasmid-Mediated Quinolone Resistance

    In the 1990s quinolone resistance increased in parallel with increased quinolone utilization (1) and also with the emergence of plasmid-mediated quinolone resistance. The fi rst type of plasmid-mediated resist...

    George A. Jacoby in Antimicrobial Drug Resistance (2009)

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    Chapter

    History of Drug-Resistant Microbes

    Resistance to antimicrobial agents has been recognized since the dawn of the antibiotic era. Paul Ehrlich, the father of modern chemotherapy, observed that, during treatment of trypanosome infections, organism...

    George A. Jacoby in Antimicrobial Drug Resistance (2009)