4 Result(s)
within
Georg Fluegen
Oncology
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Article
Open AccessUltra-sensitive CTC-based liquid biopsy for pancreatic cancer enabled by large blood volume analysis
The limited sensitivity of circulating tumor cell (CTC) detection in pancreatic adenocarcinoma (PDAC) stems from their extremely low concentration in the whole circulating blood, necessitating enhanced detecti...
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Article
Open AccessDistribution of gastrointestinal neuroendocrine tumors in Europe: results from a retrospective cross-sectional study
Gastrointestinal (non-pancreatic) neuroendocrine tumors (GI-NETs) represent a rare but increasingly common tumor entity. Prognosis and biological behavior of these tumors is extremely heterogenous and largely ...
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Article
Open AccessDisseminated tumour cells with highly aberrant genomes are linked to poor prognosis in operable oesophageal adenocarcinoma
Chromosomal instability (CIN) has repeatedly been identified as a prognostic marker. Here we evaluated the percentage of aberrant genome per cell (PAG) as a measure of CIN in single disseminated tumour cells (...
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Article
Open AccessSnail1 expression in colorectal cancer and its correlation with clinical and pathological parameters
Snail1 is a transcription regulator of E-cadherin. The loss of E-cadherin seems to be a crucial step in the process of Epithelial-mesenchymal transition (EMT). EMT initiates invasion and proliferation in many ...
