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  1. No Access

    Article

    LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway

    Abnormal phenotype switch in vascular smooth muscle cells (VSMCs) plays an important role in the initiation and progression of vascular proliferative diseases. Annexin A2 (ANXA2), related to the pro-inflammato...

    Lan Cheng, Huan Wang, ReneNfornah Maboh… in Journal of Cardiovascular Translational Re… (2022)

  2. No Access

    Article

    ACSL4 dictates ferroptosis sensitivity by sha** cellular lipid composition

    ACSL4 is critical for induction of ferroptosis, a programmed form of necrotic cell death, through the production of long polyunsaturated fatty acids that can be inhibited in an in vivo ferroptosis model with a sm...

    Sebastian Doll, Bettina Proneth, Yulia Y Tyurina… in Nature Chemical Biology (2017)

  3. No Access

    Article

    Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

    Arachidonyl and adrenoyl PE phospholipids generated by ACSL4, an acyl-CoA synthase, are doubly or triply oxidized by lipoxygenases and other iron-containing sources of oxidation to promote ferroptotic cell death.

    Valerian E Kagan, Gaowei Mao, Feng Qu… in Nature Chemical Biology (2017)

  4. No Access

    Article

    N-acetyl-l-cysteine increases MnSOD activity and enhances the recruitment of quiescent human fibroblasts to the proliferation cycle during wound healing

    The rebuilding of the connective tissue during wound healing requires the recruitment of fibroblasts to the wound area as well as reentry of quiescent fibroblasts to the proliferative cycle. Whether this proce...

    Gaowei Mao, Monali Goswami, Amanda L. Kalen… in Molecular Biology Reports (2016)