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Article
Effect of process parameters on filling behavior of PMMA in hot embossing
This study aims to evaluate the effects of process parameters and feature size on filling behavior of polymethyl methacrylate (PMMA) in rapid hot embossing. The filling behavior of PMMA was characterized by an...
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Article
Input/output data-based adaptive super-twisting sliding mode control for multi-motor servo systems
This paper studies the model reconstruction and high precision control problem of multi-actuator systems, which has a too complex traditional nonlinear dynamic model for controller design. An input/output data...
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Article
Open AccessA comprehensive workflow for optimizing RNA-seq data analysis
Current RNA-seq analysis software for RNA-seq data tends to use similar parameters across different species without considering species-specific differences. However, the suitability and accuracy of these tool...
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Article
Preliminary safety analysis for a heavy water-moderated molten salt reactor
The heavy water-moderated molten salt reactor (HWMSR) is a newly proposed reactor concept, in which heavy water is adopted as the moderator and molten salt dissolved with fissile and fertile elements is used a...
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Article
Unraveling Estrogen and PCSK9’s Roles in Lipid Metabolism Disorders among Ovariectomized Mice
We explore the interaction between estrogen and PCSK9 and their collective impact on lipid metabolism, especially concerning the regulation of low-density lipoprotein receptor levels. Utilizing both animal and...
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Article
Recognition of autism spectrum disorder in children based on electroencephalogram network topology
Although our knowledge of autism spectrum disorder (ASD) has been deepened, the accurate diagnosis of ASD from normal individuals is still left behind. In this study, we proposed to apply the spatial pattern o...
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Article
Acetylene/argon mixture plasma to build ultrathin carbon bridge of CFx/C/MnO2 for high-rate lithium primary battery
Forming an ultrathin conducting layer on a fluorinated carbon (CFx) surface for reducing severe electrochemical polarization in lithium/fluorinated carbon primary batteries (Li/CFx) remains a considerable challen...
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Article
Open AccessA study on the application of radiomics based on cardiac MR non-enhanced cine sequence in the early diagnosis of hypertensive heart disease
The prevalence of hypertensive heart disease (HHD) is high and there is currently no easy way to detect early HHD. Explore the application of radiomics using cardiac magnetic resonance (CMR) non-enhanced cine ...
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Article
Open AccessOptimization of preparation conditions and performance of a new degradable soil water retaining agent
Using polyaspartic acid (PAsp) and bentonite (BT) as the main raw materials, a new type of degradable soil water retaining agent (PAsp-AA/BT) was synthesized by microwave radiation. The optimum synthesis condi...
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Article
Open AccessMemory of elastic collisions drives high minority spin and oscillatory entropy in underdamped chiral spinners
Inertial underdamped collisions preserve the memory of physical parameters that existed before the collision, leading to phenomena usually unseen in overdamped systems. Here we probe the less studied inertial ...
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Article
Cell subtype-specific effects of genetic variation in the Alzheimer’s disease brain
The relationship between genetic variation and gene expression in brain cell types and subtypes remains understudied. Here, we generated single-nucleus RNA sequencing data from the neocortex of 424 individuals...
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Article
Adapting Across Domains via Target-Oriented Transferable Semantic Augmentation Under Prototype Constraint
The demand for reducing label annotation cost and adapting to new data distributions gives rise to the emergence of domain adaptation (DA). DA aims to learn a model that performs well on the unlabeled or scarc...
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Article
Stochastic Simulation of Thermal Residual Stress in Environmental Barrier Coated 2.5D Woven Ceramic Matrix Composites
This paper deals with the evolution of thermal residual stress (TRS) in Ceramic Matrix Composites (CMC) with environmental barrier coating (EBC) for aeroengine applications. In particular, in hot section compo...
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Article
Open AccessThe cavitation characteristics of aerospace high-speed centrifugal pumps with different tip clearance
This study investigates the Tip Clearance Cavitation (TCC) characteristics of three different Tip Clearances (TC) (0.4, 0.6, 0.8) and five inlet negative pressure conditions Pj = (− 20–60)kPa to improve the re...
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Article
Open AccessOxymatrine protects articular chondrocytes from IL-1β-induced damage through autophagy activation via AKT/mTOR signaling pathway inhibition
Osteoarthritis (OA) is a common degenerative joint disease characterized by persistent articular cartilage degeneration and synovitis. Oxymatrine (OMT) is a quinzolazine alkaloid extracted from the traditional...
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Article
Open AccessClinical evidence for efficacy of pembrolizumab in MSI-H and TMB-H advanced solid tumor: results from three cancer centers in China
Pembrolizumab has been indicated in the treatment of solid tumors with high frequency microsatellite instability (MSI-H) or high tumor mutational burden (TMB-H); however, real-world data on the effectiveness o...
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Article
An evaluation method for nuclear radiation detection performance of glass scintillator
Glass is a potential choice for the scintillator in Hadronic calorimetry (HCAL) of the CEPC. It requires sophisticated instruments and suitable methods to obtain scintillation properties of the glasses in the ...
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Article
Controls on the effect of impact scra** on high-position and long-runout landslides
Landslides in mountainous areas act as an important control on morphological landscape evolution and represent a major natural hazard. The dynamic characteristics of a landslide directly relate to the distance...
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Article
Modified deep deterministic policy gradient based on active disturbance rejection control for hypersonic vehicles
For the attitude control of hypersonic vehicles, a control scheme based on linear active disturbance rejection (LADRC) and modified deep deterministic policy gradient (MDDPG) is proposed. Firstly, LADRC is use...
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Article
H3K4 Trimethylation Mediate Hyperhomocysteinemia Induced Neurodegeneration via Suppressing Histone Acetylation by ANP32A
Homocysteine (Hcy) is an independent and serious risk factor for dementia, including Alzheimer’s disease (AD), but the precise mechanisms are still poorly understood. In the current study, we observed that the...
