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Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages

Hypoxia is a hallmark of cancer that is strongly associated with invasion, metastasis, resistance to therapy and poor clinical outcome. Tumour hypoxia affects immune responses and promotes the accumulation of ...

Roman Huber, Barbara Meier, Atsushi Otsuka, Gabriele Fenini… in Scientific Reports (2016)