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  1. No Access

    Article

    Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity

    Cultured cell lines are the workhorse of cancer research, but the extent to which they recapitulate the heterogeneity observed among malignant cells in tumors is unclear. Here we used multiplexed single-cell R...

    Gabriela S. Kinker, Alissa C. Greenwald, Rotem Tal, Zhanna Orlova… in Nature Genetics (2020)

  2. Article

    Open Access

    Rhythmic expression of the melatonergic biosynthetic pathway and its differential modulation in vitro by LPS and IL10 in bone marrow and spleen

    Daily oscillation of the immune system follows the central biological clock outputs control such as melatonin produced by the pineal gland. Despite the literature showing that melatonin is also synthesized by ...

    Marlina O. Córdoba-Moreno, Ewerton da Silva de Souza… in Scientific Reports (2020)

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