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  1. No Access

    Article

    Prognostic value of evoked potentials and clinical grading in primary subarachnoid haemorrhage

    In a retrospective study of 64 patients suffering from primary subarachnoid haemorrhage (SAH), the clinical grading according to Hunt and Hess as well as the initial findings of brainstem auditory evoked poten...

    W. F. Haupt, C. Hojer, G. Pawlik in Acta Neurochirurgica (1995)

  2. No Access

    Chapter and Conference Paper

    Epileptogene Herde bei Temporallappenepilepsie: Dissoziation von Durchblutung und Stoffwechsel

    Der Erfolg epilepsiechirurgischer Eingriffe hängt wesentlich von der Genauigkeit der prächirurgischen Lokalisation epileptogener Zonen ab. Daher werden zahlreiche diagnostische Verfahren eingesetzt, die eine F...

    G. R. Fink, G. Pawlik, B. Szelies, H. Stefan… in Topographische Diagnostik des Gehirns (1995)

  3. No Access

    Chapter and Conference Paper

    Sprachaktivierungs-PET und iktuale SPECT-Untersuchungen zur Lokalisation epileptogener Zonen bei Temporallappenepilepsie

    Begrenzte epilepsiechirurgische Eingriffe zur Behandlung pharmakotherapieresistenter lokalisationsbezogener Anfallsleiden gewinnen insbesondere bei Temporallappenepilepsien (TLE) zunehmend an klinischer Bedeut...

    G. Pawlik, G. R. Fink, H. Stefan, H. Feistel… in Topographische Diagnostik des Gehirns (1995)

  4. No Access

    Article

    Changing patterns of glucose metabolism during the course of subacute sclerosing panencephalitis as measured with18FDG-positron-emission tomography

    18FDG-positron emission tomography performed at different stages in the course of subacute sclerosing panencephalitis revealed a changing pattern of metabolic disturbance. In clinical stage II patients the infla...

    M. Huber, G. Pawlik, S. Bamborschke, G. R. Finke, H. Karbe… in Journal of Neurology (1992)

  5. No Access

    Chapter and Conference Paper

    Positron Emission Tomography Activation Studies in Neurological Patients

    The quantitative imaging of the hemodynamic and metabolic changes occurring in brain regions responding to distinct stimulation or involved in tie performance of specific tasks is one of the most intriguing ap...

    G. Pawlik, G. R. Fink, U. Pietrzyk, M. Grond, W.-D. Heiss in Stimulated Cerebral Blood Flow (1992)

  6. No Access

    Chapter and Conference Paper

    Positron Emission Tomography in Cerebrovascular Disease: Implications for Therapy?

    The complex mechanisms involved in ischemic cell injury must be taken into consideration when develo** a rational basis of treatment of ischemic stroke and vasular dementia. While focal perfusional disturban...

    W.-D. Heiss, V. Holthoff, G. Pawlik, C. Beil, M. Neveling in Cerebral Ischemia and Dementia (1991)

  7. No Access

    Chapter and Conference Paper

    Positron Emission Tomography in Nimodipine-Treated Patients with Acute Ischemic Stroke

    In patients with acute cerebral infarction, immediate treatment is aimed at preventing further irreversible damage and restoring functionally impaired but structurally intact tissue. This has focused attention...

    V. A. Holthoff, W.-D. Heiss, G. Pawlik, M. Neveling in Nimodipine (1991)

  8. No Access

    Article

    PET studies of dopamine receptor distribution using [18F]fluoroethylspiperone: findings in disorders related to the dopaminergic system

    PET studies of dopamine D2-receptor binding were performed in thirty patients with various disorders related to the dopaminergic system and in six healthy controls. Uptake of [18F]fluoroethylspiperone in caudate ...

    K. Wienhard, H. H. Coenen, G. Pawlik… in Journal of Neural Transmission / General S… (1990)

  9. No Access

    Chapter

    PET scanning for the detection of Alzheimer’s disease

    At present, PET is the only technology affording the quantitative, three-dimensional imaging of various aspects of brain function. Since function and metabolism are coupled, and since glucose is the dominant s...

    W.-D. Heiss, B. Szelies, R. Adams… in Early Markers in Parkinson’s and Alzheimer… (1990)

  10. No Access

    Chapter

    PET criteria for diagnosis of Alzheimer’s disease and other dementias

    At present, PET is the only technology affording the quantitative, three-dimensional imaging of various aspects of brain function. Since function and metabolism are coupled, and since glucose is the dominant s...

    Prof. Dr. W.-D. Heiss, B. Szelies, R. Adams… in Alzheimer’s Disease. Epidemiology, Neuropa… (1990)

  11. No Access

    Chapter and Conference Paper

    PET in the Differential Diagnosis and Evaluation of Treatment in Dementias

    Under normal conditions, function, metabolism and blood flow of the central nervous system are closely interlinked. Therefore, the cerebral structures involved in different activities can be demonstrated by st...

    W.-D. Heiss, K. Herholz, G. Pawlik… in Imaging of Brain Metabolism Spine and Cord… (1989)

  12. No Access

    Chapter

    Positron Emission Tomography and Neuropsychological Function

    The cerebral localization not only of elementary sensory or motor functions but also of complex mental activities and human behavior has been dominated traditionally by neuroanatomic concepts derived from corr...

    G. Pawlik, W.-D. Heiss in Neuropsychological Function and Brain Imaging (1989)

  13. No Access

    Chapter

    Ergebnisse mit der Positronen-Emissions-Tomographie bei zerebralen Alterskrankheiten

    Aufgrund der engen Kopplung von Funktion, Stoffwechsel und Durchblutung im zentralen Nervensystem können mittels Studien dieser physiologischen Parameter die an verschiedenen Aktivitäten beteiligten Hirnstrukt...

    W. D. Heiss, B. Szelies, G. Pawlik… in Verhandlungen der Deutschen Gesellschaft f… (1989)

  14. No Access

    Chapter and Conference Paper

    Positronenemissionstomographie in der Differentialdiagnostik und Therapiekontrolle dementieller Erkrankungen

    Die Entwicklung computergesteuerter tomographischer Darstellungsmethoden hat die Medizintechnik des letzten Jahrzehntes entscheidend geprägt. Mit Einführung der axialen Röntgencomputertomographie (CT) 1973 dur...

    B. Szelies, K. Herholz, G. Pawlik, W.-D. Heiss in Dementielle Erkrankungen (1988)

  15. No Access

    Chapter

    PET-Befunde bei dementiellen Erkrankungen: Beiträge zur Differentialdiagnose und Objektivierung therapeutischer Effekte

    Aufgrund der engen Kopplung von Funktion, Stoffwechsel und Durchblutung im zentralen Nervensystem können mittels Studien dieser physiologischen Parameter die an verschiedenen Aktivitäten beteiligten Hirnstrukt...

    W.-D. Heiss, K. Herholz, G. Pawlik, I. Hebold… in Wirkungen und Wirksamkeit von Nootropika (1988)

  16. No Access

    Article

    Functional and morphological abnormalities in temporal lobe epilepsy: a comparison of interictal and ictal EEG, CT, MRI, SPECT and PET

    Ten patients suffering from drug-resistant complex partial seizures, with EEG abnormalities in the temporal region, were studied by means of non-invasive electrophysiological techniques (video-monitored, 16-ch...

    H. Stefan, G. Pawlik, H. G. Böcher-Schwarz, H. J. Biersack, W. Burr… in Journal of Neurology (1987)

  17. No Access

    Book

    Clinical efficacy of positron emission tomography

    Proceedings of a workshop held in Cologne, FRG, sponsored by the Commission of the European Communities as advised by the Committee on Medical and Public Health Research

    W.-D. Heiss, G. Pawlik, K. Herholz… in Developments in Nuclear Medicine (1987)

  18. No Access

    Chapter

    Localizing Epileptic Foci by PET

    In most experimental models of focal and generalized epileptic seizures a substantial increase of glucose metabolism has been observed in those brain structures which were involved in the pathological activity...

    K. Herholz, G. Pawlik, W. Staffen… in Clinical efficacy of positron emission tom… (1987)

  19. No Access

    Chapter and Conference Paper

    New Diagnostic Tools for Localizing the Epileptic Focus: Positron Emission Tomography of Cerebral Glucose Metabolism and Magnetic Resonance Imaging in Patients with Complex Partial Seizures

    The need for presurgical localization of the epileptic focus is obvious. In patients with drug-resistant complex partial seizures, positron emission tomography (PET) and magnetic resonance imaging (MRI) are li...

    H. G. Böcher-Schwarz, H. Stefan, G. Pawlik… in Regulation of Cerebral Blood Flow and Meta… (1987)

  20. No Access

    Chapter and Conference Paper

    Determination of Regional Glucose Metabolism in the Brain by Positron Emission Tomography Using 18F-Fluoro-2-deoxy-D-glucose

    Since the energy requirement of the brain is supplied almost exclusively by glucose, the functional state of the tissue can be estimated and quantitatively demonstrated by reference to the glucose metabolism. ...

    W.-D. Heiss, K. Herholz, G. Pawlik… in Regulation of Cerebral Blood Flow and Meta… (1987)

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