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Article
Open AccessThe economic burden of pediatric growth hormone deficiency in Italy: a cost of illness study
Growth hormone deficiency (GHD) is a rare condition with a worldwide prevalence of 1 patient in 4000 to 10,000 live births, placing a significant economic burden on healthcare systems. The aim of this study is...
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Article
Open AccessQuality of life in children and adolescents with growth hormone deficiency and their caregivers: an Italian survey
The aim of this study was to produce evidence on quality of life (QoL) among Italian growth hormone deficiency (GHD) children and adolescents treated with growth hormone (GH) and their parents.
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Article
Open AccessAre glucose and insulin levels at all time points during OGTT a reliable marker of diabetes mellitus risk in pediatric obesity?
Childhood overweight and obesity associated with insulin resistance and metabolic syndrome represent the new global pandemic and the main causative factors for dysglycemia, prediabetes, and Type 2 Diabetes Mel...
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Article
Multicentric Italian case–control study on 25OH vitamin D levels in children and adolescents with Prader-Willi syndrome
25OHD levels in patients with Prader-Willi Syndrome (PWS), the most frequent cause of genetic obesity with a peculiar fat mass distribution, are still debated. Insulin resistance (IR), Body Mass Index-SDS (BMI...
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Article
Prevention of delayed emesis induced by moderately emetogenic chemotherapy in patients with acute emesis
The rates of delayed nausea and vomiting by moderately emetogenic chemotherapy in patients with previous experience of acute emesis are usually quite high. This is a pilot study aiming to evaluate the safety o...
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Article
The role of minimal surgery with renal preservation in abnormal complete duplex systems
Among 36 children, mostly less than 1 year of age, referred for a complete duplex-system anomaly, 18 were diagnosed before birth by obstetrical ultrasonography where a diagnosis of dilated upper urinary tract...
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Chapter
Chronobiology of the Haemostatic System
When a blood vessel is cut or damaged, the blood in its vicinity tends to solidify. The principal events of this process, known as haemostasis, are: (1) the constriction of the damaged vessel, (2) the depositi...
