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Open AccessDonanemab (LY3002813) Phase 1b Study in Alzheimer’s Disease: Rapid and Sustained Reduction of Brain Amyloid Measured by Florbetapir F18 Imaging
Donanemab (LY3002813) is an IgG1 antibody directed at an N-terminal pyroglutamate of amyloid beta epitope that is present only in brain amyloid plaques.
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Article
Amplified Ras-MAPK signal states correlate with accelerated EGFR internalization, cytostasis and delayed HER2 tumor onset in Fer-deficient model systems
The non-receptor tyrosine kinase Fer belongs to a distinct subfamily of F-BAR domain containing kinases implicated in vesicular trafficking and signaling downstream of adhesion and growth factor receptors. Tar...
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Article
Aggressive management leads to improved survival in patients with small cell lung carcinoma
Small cell lung carcinoma (SCLC) accounts for 17–25% of all cases of lung cancer, and remains the most lethal form of this disease.
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Irish thoracic society
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Article
A quality control programme for performance evaluation of dynamic replacement of organic soil deposits
Dynamic replacement (DR) is a relatively new ground-modification technique that has been used successfully to stabilize organic soil deposits by replacing the organic soil with sand columns. A full-scale DR fi...
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Article
A quality control programme for performance evaluation of dynamic replacement of organic soil deposits
Dynamic replacement (DR) is a relatively new ground-modification technique that has been used successfully to stabilize organic soil deposits by replacing the organic soil with sand columns. A full-scale DR fi...
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Article
Impacts of intensive dairy production on smallholder farm women in coastal Kenya
Welfare impacts of an intensive dairy technology package on women and their families are investigated on 32 smallholder crop-livestock farms in the sub-humid zone off Kilifi District, Coast Province, Kenya. Fa.....