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Article
Open AccessUpdate on the Treatment of Idiopathic Hypersomnia
Idiopathic hypersomnia is an incapacitating disorder with a profound impact on daytime performance and quality of life. The most commonly used treatment modalities are lifestyle advice and pharmacological ther...
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Article
Carotid body tumors are not associated with an increased risk for sleep-disordered breathing
Tumors in the carotid bodies may interfere with their function as peripheral chemoreceptors. An altered control of ventilation may predispose to sleep-disordered breathing. This study aimed to assess whether p...
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Article
Open AccessDisturbed subjective sleep characteristics in adult patients with long-standing type 1 diabetes mellitus
Decreased sleep duration and/or impaired sleep quality negatively influence glucoregulation. The aim of this study was to assess subjective sleep characteristics in patients with type 1 diabetes, to relate sle...
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Chapter
Treatment of Narcolepsy
The core problem of patients suffering from narcolepsy is their inability to remain fully alert or even awake during the day. Paradoxically, narcolepsy patients may also have difficulty remaining asleep during...
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Poster abstracts
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Article
Open AccessDoes modafinil enhance activity of patients with myotonic dystrophy?
We performed a double-blind placebo-controlled crossover study in 13 patients with myotonic dystrophy to address the question whether modafinil, known to improve hypersomnolence in myotonic dystrophy, may impr...
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Article
Neonatale myoclonieën na maternaal clomipramine-gebruik tijdens de zwangerschap
We describe a newborn who developed stimulussensitive symmetrical myoclonic jerks on the fifth postnatal day. These myoclonic jerks did not respond to anti-epileptic drugs (phenobarbital and clonazepam) and el...
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Article
Neurogenesis in the basal forebrain in the Chinese hamster (Cricetulus griseus)
In the present study the morphogenesis of the ventricular ridges, i.e. the site of origin for neurons in the basal ganglia and various related basal forebrain structures, has been studied in the Chinese hamste...