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The detection of K-ras mutations in colorectal cancer using the amplification-refractory mutation system

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  1. Article

    Open Access

    Current status and future potential of somatic mutation testing from circulating free DNA in patients with solid tumours

    Genetic alterations can determine the natural history of cancer and its treatment response. With further advances in DNA sequencing technology, multiple novel genetic alterations will be discovered which could...

    K. L. Aung, R. E. Board, G. Ellison, E. Donald, T. Ward, G. Clack… in The HUGO Journal (2010)

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  2. Article

    Open Access

    Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study

    This study investigated the potential clinical utility of circulating free DNA (cfDNA) as a source of BRAF mutation detection in patients enrolled into a phase II study of AZD6244, a specific MEK1/2 inhibitor, in...

    R E Board, G Ellison, M C M Orr, K R Kemsley, G McWalter… in British Journal of Cancer (2009)

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  3. Article

    Open Access

    Identification of potential diagnostic markers of prostate cancer and prostatic intraepithelial neoplasia using cDNA microarray

    The identification of novel genes or groups of genes expressed in prostate cancer may allow earlier diagnosis or more accurate staging of the disease. We describe the assembly and use of a 1877-member microarr...

    J H Bull, G Ellison, A Patel, G Muir, M Walker, M Underwood… in British Journal of Cancer (2001)

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