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Article
Open AccessReversal of MYB-dependent suppression of MAFB expression overrides leukaemia phenotype in MLL-rearranged AML
The transcription factor MYB plays a pivotal role in haematopoietic homoeostasis and its aberrant expression is involved in the genesis and maintenance of acute myeloid leukaemia (AML). We have previously demo...
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Chapter and Conference Paper
Satellite IoT for TT&C and Satellite Identification
The new small satellite constellations require real-time and low cost satellite operations for telemetry, tracking and control (TT&C) of all the space assets. Nowadays, these small satellites are launched with...
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Article
COVID-19 lockdown negatively impacted on adherence to denosumab therapy: incidence of non-traumatic fractures and role of telemedicine
Coronavirus disease (COVID-19) lockdowns have impacted on management of osteoporosis and the use of telemedicine is increasingly widespread albeit supported by little evidence so far. The aim of the study is t...
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Article
Effects of acute and sub-acute hypobaric hypoxia on oxidative stress: a field study in the Alps
High altitude results in lower barometric pressure and hence partial pressure of O2 decrease can lead to several molecular and cellular changes, such as generation of reactive oxygen species (ROS). Electron Param...
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Article
Open AccessProceedings of the 23rd Paediatric Rheumatology European Society Congress: part two
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Article
Nickel Free-Diet Enhances the Helicobacter pylori Eradication Rate: A Pilot Study
The Helicobacter pylori eradication rate with standard triple therapy is very low. H. pylori is known to require the nickel-containing metalloenzymes urease and NiFe-hydrogenase to survive at the low pH environme...
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Chapter
Regulation of the Hedgehog Morphogene Gradient
The development of a multicellular organism is controlled by a genetic program that manifests itself in proliferation, cell differentiation, and apoptosis, leading to the formation of functional organs. A smal...
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Article
Prothrombotic state at hospital discharge increases 1-year mortality in pneumonia and sepsis survivors
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Reference Work Entry In depth
The Phosphoinositides
Phosphatidylinositol (PtdIns) is a membrane phospholipid that comprises the polar myo-inositol hexahydroxycyclohexane headgroup attached via a phosphoester bond to sn-1,2-diacylgycerol 3-phosphate. The phosphoino...
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Article
Membrane traffic in the secretory pathway
Membrane trafficking is crucial in the homeostasis of the highly compartmentalized eukaryotic cells. This compartmentalization occurs both at the organelle level, with distinct organelles maintaining their ide...
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Article
Allocating point-to-point connections over point-to-multipoint optical channels
Optical channels are currently able to carry 10 Gbit/s and even 40 Gbit/s traffic flows. However, it is not usual to have such amounts of traffic between any pair of client nodes. This article proposes using p...
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Chapter and Conference Paper
The Wind of FU Orionis: Modelling the Atmosphere
The FU Orionis objects are a class of accreting pre-main sequence stars that undergo dramatic outbursts in their brightness. They also show signatures of very strong winds, as indicated by the P Cygni profiles...
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Chapter
Response of Three Compost-based Substrates to Different Irrigation and Fertilization Regimes in Poinsettia (Euphorbia pulcherrima Willd.)
Since 1985, the research section of Minoprio Foundation has been testing different composted materials of vegetable origin as components of growing media for ornamental pot plants. The study of the relationshi...
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Article
Low-temperature specific heats of lanthanum and yttrium phosphate glasses
The specific heats of (R2O3) x (P2O5)1−x glasses containing high concentrations of La3+ and Y3+ ions have been measured between 1.5K and 30K. It is shown that, i...
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Article
Arthroscopic Surgery of the Shoulder
Arthroscopy of the shoulder is well established as a diagnostic procedure. It carries a greater degree of accuracy than conventional imaging techniques and in addition allows the assessment of instability and ...