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Article
Percutaneous vertebroplasty and balloon kyphoplasty in the treatment of osteoporotic vertebral fractures: a prospective randomized comparison
The purpose of this study is to compare the efficacy and safety of percutaneous vertebroplasty (PVP) and balloon kyphoplasty (BKP) in the treatment of osteoporotic vertebral compression fractures.
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Article
Open AccessA Rationale for the Use of Clotted Vertebral Bone Marrow to Aid Tissue Regeneration Following Spinal Surgery
Vertebral body bone marrow aspirate (V-BMA), easily accessible simultaneously with the preparation of the site for pedicle screw insertion during spinal procedures, is becoming an increasingly used cell therap...
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Article
Navigation-assisted surgery for tumors of the spine
Computer-assisted navigation systems are largely used for pedicle screws positioning in degenerative and traumatic spine surgery. In oncologic spine surgery its use is still develo** and could be extended fo...
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Article
Le neoplasie del tratto lombare: trattamento chirurgico
Primary tumors of the lumbar spine are very rare and can be treated by an oncologically appropriate surgery if properly diagnosed and staged. Surgical treatment is greatly conditioned by generally unresectable...
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Article
Il trattamento percutaneo dei crolli osteoporotici del corpo vertebrale
The Authors present a retrospective review of 59 consecutive patients who underwent polymethylmethacrylate percutaneous vertebroplasty for vertebral compression fractures due to osteoporosis. In the immediate ...
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Article
Human mesenchymal stem cells and biomaterials interaction: a promising synergy to improve spine fusion
Spine fusion is the gold standard treatment in degenerative and traumatic spine diseases. The bone regenerative medicine needs (i) in vitro functionally active osteoblasts, and/or (ii) the in vivo induction of...
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Article
Minimally invasive percutaneous fixation in the treatment of thoracic and lumbar spine fractures
We studied 51 patients with 64 fractures of the thoracolumbar and lumbar spine undergoing the surgical treatment by percutaneous trans-pedicular fixation and stabilization with minimally invasive technique. Pa...
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Article
Le “cage” in carbonio (CFRP) favoriscono una maggiore proliferazione e una migliore distribuzione cellulare di quelle in polietere-etereketone (PEEK). Analisi mediante un modello innovativo per lo studio in vitro dei biomateriali
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Article
Lumbar stenosis. Treatment strategy: When should one perform additional stabilization and/or fusion after posterior decompression?
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Article
Patellar height after high tibial osteotomy
We analysed two series of patients affected by unicompartmental arthrosis or axial malalignment of the knee treated with two different techniques of high tibial osteotomy. Forty-seven knees were treated with ...
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Article
Evaluation of radiolucency condition in total hip arthroplasty: a statistical comparison of the diagnostic capability of digitised image vs conventional X-ray film
This work analyses the diagnostic capability of radiographic images taken from patients with total hip arthroplasty and visualised on monitor. Images were obtained with digital acquisition of conventional X-r...
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Article
Inhibition of HIV-1 replication by a Tat transdominant negative mutant in human peripheral blood lymphocytes from healthy donors and HIV-1-infected patients
It was previously shown that a tat mutant (tat22) where cysteine 22 is substituted by glycine behaves as a transdominant negative mutant in Jurkat T cells lytically or latently infected by HIV-1. In this study we...
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Article
Studies on the effect of the combined expression of anti-tat and anti-rev genes on HIV-1 replication
A series of retroviral vectors with potential anti-tat and anti-rev activity was developed. Vectors containing a tat transdominant negative mutant (tat22/37) and an RRE decoy in different positions, directed by t...
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Article
A BK virus episomal vector for constitutive high expression of exogenous cDNAs in human cells
A BK virus (BKV) episomal vector (pRPneoCMV) was constructed for expression of cDNAs under control of the cytomegalovirus (CMV) immediate-early promoter. Transfection of pRPneoCMV for expression of the chloramphe...
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Article
Factors affecting amplification of BK virus episomal vectors in human cells
Analysis of factors determining replication of BK virus (BKV) episomal vectors in human cells showed that vector copy number was related to the level of BKV T antigen expression. T antigen was synthesized effi...
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Article
New BK virus episomal vector for complementary DNA expression in human cells
The properties of pRP-c, a new vector for complementary DNA (cDNA) expression, are described. The vector contains the early region and replication origin of BK virus (BKV), a human papovavirus. Due to the pres...
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Article
Oncogenity of BK virus for immunosuppressed hamsters
Tumors were induced by BK virus (BKV) inoculated intravenously in 3-week-old Syrian golden hamsters immunosuppressed with anti-lymphocyte serum or methylprednisolone acetate alone or in association with γ-radi...
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Chapter
Hepatocyte Targeting of Antiviral Drugs Coupled to Galactosyl-Terminating Glycoproteins
This chapter deals with the possibility of specifically introducing inhibitors of DNA synthesis into hepatocytes by conjugation to galactosyl-terminating glycoproteins which are selectively taken up by parench...
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Article
Analysis of BK virus-transformed cells and BK virus-induced tumors by DNA-DNA reassociation kinetics
BK virus (BKV)-transformed cells and BKV-induced tumors as well asin vitro derived tumor cell lines were all found to contain BKV DNA sequences when analysed by DNA-DNA reassociation kinetics. In transformed cell...
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Article
Differences between BK virus and Simian Virus 40 structural proteins analysed by isoelectric focusing
Structural proteins of purified BK virus and Simian Virus 40 were separated by isoelectric focusing into four components. Structural polypeptides of Simian Virus 40 had a lower isoelectric point than those of ...