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  1. No Access

    Article

    Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98–HOXA9-induced myeloid disease

    Acute myeloid leukemia (AML) occurs when multiple genetic aberrations alter white blood cell development, leading to hyperproliferation and arrest of cell differentiation. Pertinent animal models link in vitro st...

    A P Deveau, A M Forrester, A J Coombs, G S Wagner, C Grabher, I C Chute… in Leukemia (2015)

  2. No Access

    Article

    Investigation of Green Emitting Monolithic II-VI Vertical Cavity Surface Emitting Laser

    In this paper, we are investigating the growth of a ZnSe based vertical cavity surface emitting laser (VCSEL). Undoped and p-type doped distributed Bragg reflectors (DBRs) with reflectivities exceeding 99% hav...

    C. Kruse, G. Alexe, R. Kröger, M. Klude, H. Heinke… in MRS Online Proceedings Library (2011)

  3. No Access

    Article

    PCA and Clustering Reveal Alternate mtDNA Phylogeny of N and M Clades

    Phylogenetic trees based on mtDNA polymorphisms are often used to infer the history of recent human migrations. However, there is no consensus on which method to use. Most methods make strong assumptions which...

    G. Alexe, R. Vijaya Satya, M. Seiler, D. Platt, T. Bhanot… in Journal of Molecular Evolution (2008)

  4. No Access

    Article

    Analysis of breast cancer progression using principal component analysis and clustering

    We develop a new technique to analyse microarray data which uses a combination of principal components analysis and consensus ensemble k-clustering to find robust clusters and gene markers in the data. We apply o...

    G. Alexe, G. S. Dalgin, S. Ganesan, C. DeLisi, G. Bhanot in Journal of Biosciences (2007)

  5. No Access

    Article

    Energetics of Nucleation for the Icosahedral Al–Mn Phase in HTSD-Deposited Thin Films

    The cohesive energy of the Al–Mn Mackay icosahedron (MI) was estimated for different variants of chemical order, using pair-bonding energies. This problem is related to the nucleation of i-AlMn phase in sequen...

    R. Manaila, G. Alexe, P. B. Barna, C. Giusca, A. Devenyi in Structural Chemistry (2002)