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  1. No Access

    Article

    Development of quality of life in patients undergoing allogeneic stem cell transplantation with regard to anxiety, depression and resilience

    A Schumacher, C Sauerland, G Silling, W E Berdel, M Stelljes… in Bone Marrow Transplantation (2017)

  2. No Access

    Article

    Serial assessment of pulmonary lesion volume by computed tomography allows survival prediction in invasive pulmonary aspergillosis

    Serial chest CT is the standard of care to establish treatment success in invasive pulmonary aspergillosis (IPA). Data are lacking how response should be defined.

    J. J. Vehreschild, C. P. Heussel, A. H. Groll… in European Radiology (2017)

  3. No Access

    Article

    Treatment strategies in patients with AML or high-risk myelodysplastic syndrome relapsed after Allo-SCT

    Non-relapse mortality after Allo-SCT has significantly decreased over the last years. Nevertheless, relapse remains a major cause for post SCT mortality in patients with AML and high-risk myelodysplastic syndr...

    T Sauer, G Silling, C Groth, F Rosenow, U Krug, D Görlich… in Bone Marrow Transplantation (2015)

  4. No Access

    Article

    Molecular monitoring in NUP214-ABL-positive T-acute lymphoblastic leukemia reveals clonal diversity and helps to guide targeted therapy

    S Koschmieder, T Burmeister, M Brüggemann, A Berkemeier, S Volpert, P Wieacker… in Leukemia (2014)

  5. No Access

    Article

    CD34+ lineage specific donor cell chimerism for the diagnosis and treatment of impending relapse of AML or myelodysplastic syndrome after allo-SCT

    After allo-SCT, analysis of CD34+ lineage-specific donor cell chimerism (DCC) is a sensitive method for monitoring minimal residual disease in patients with AML or myelodysplastic syndrome (MDS) with CD34 express...

    F Rosenow, A Berkemeier, U Krug, C Müller-Tidow, J Gerss… in Bone Marrow Transplantation (2013)

  6. No Access

    Article

    Allogeneic stem cell transplant to eliminate germline mutations in the gene for CCAAT-enhancer-binding protein α from hematopoietic cells in a family with AML

    M Stelljes, A Corbacioglu, R F Schlenk, K Döhner, M C Frühwald, C Rossig… in Leukemia (2011)

  7. No Access

    Article

    Randomized phase III study of granulocyte transfusions in neutropenic patients

    Despite antibiotics, antifungals and haematopoietic growth factors, infections remain a major threat to neutropenic patients. To determine the role of granulocyte transfusions (GTs) in anti-infective therapy d...

    M G Seidel, C Peters, A Wacker, H Northoff, R Moog, A Boehme… in Bone Marrow Transplantation (2008)

  8. No Access

    Article

    A Prospective, Randomized Multicenter Trial of the Empirical Addition of Antifungal Therapy for Febrile Neutropenic Cancer Patients: Results of the Paul Ehrlich Society for Chemotherapy (PEG) Multicenter Trial II

    The aim of the study was to compare the efficacy of empirical antifungals in combination with broad spectrum antibiotics with that of antibiotics alone in high risk febrile neutropenic cancer patients not resp...

    X. Schiel, H. Link, G. Maschmeyer, B. Glaß, O. A. Cornely, D. Buchheidt… in Infection (2006)

  9. No Access

    Article

    Prediction of relapse of acute myeloid leukemia in allogeneic transplant recipients by marrow CD34+ donor cell chimerism analysis

    C Scheffold, M Kroeger, M Zuehlsdorf, J Tchinda, G Silling, G Bis**… in Leukemia (2004)

  10. No Access

    Chapter and Conference Paper

    TBI-Based Reduced Intensity Conditioning with Allogeneic Hematopoietic Stem Cell Transplantation (SCT) in Patients with High-Risk Hematologic Malignancies

    Conventional chemotherapy is often unsatisfactory in high-risk hematologic malignancies (Carella et al., 1993) while myeloablative chemotherapy followed by allogeneic SCT can produce durable remissions (Forman et...

    M. J. Kröger, A. Schuck, M. Kiehl… in Transplantation in Hematology and Oncology… (2003)

  11. No Access

    Chapter and Conference Paper

    Strategies for Empiric Antifungal Therapy in Neutropenic Patients

    Patients with hematological malignancies and profound neutropenia are at major risk for develo** infections and particularly fungal infections impair outcome. Although diagnostic means have been improved wit...

    G. Silling in Acute Leukemias IX (2003)

  12. No Access

    Article

    Treatment of Severe Candida Infections in High-Risk Patients in Germany: Consensus Formed by a Panel of Interdisciplinary Investigators

    Now that modern medicine can provide increasing chances of cure to patients with formerly incurable disorders, therapy-related complications play the key role in outcome. Thus, among opportunistic infections, ...

    T. Büchner, W. Fegeler, H. Bernhardt… in European Journal of Clinical Microbiology … (2002)

  13. No Access

    Chapter and Conference Paper

    Early Empiric Antifungal Treatment of Infections in Neutropenic Patients with Hematological Malignancies Comparing Fluconazole with Amphotericin B and 5-Flucytosine

    Intensification of chemotherapy in patients with hematological malignancies has improved prognosis with regard to the underlying disease. Despite advances in supportive care and antibiotic therapy, prolonged p...

    G. Silling, W. Fegeler, N. Roos, M. Essink, T. Büchner in Acute Leukemias VIII (2001)

  14. No Access

    Chapter and Conference Paper

    Early Empiric Antifungal Treatment of Infections in Neutropenic Patients Comparing Fluconazole with Amphotericin B/5-Flucytosine

    In order to improve outcome in neutropenic patients with hematological malignancies we administered i.v. antifungal agents early as part of an empiric antimicrobial regimen. Additionally, we compared the toler...

    G. Silling, W. Fegeler, N. Roos, R. Schomaker, M. Essink, T. Büchner in Acute Leukemias VI (1997)