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Article
Open AccessAttenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L
Caspase-2 represents the most conserved member of the caspase family, which exhibits features of both initiator and effector caspases. Using ribonucleoprotein (RNP)-immunoprecipitation assay, we identified the...
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Article
Open AccessFlexible alignment in 3D and its applications
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Article
Open AccessHigh expression of RelA/p65 is associated with activation of nuclear factor-κB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis
Activation of nuclear factor-κB (NF-κB) signaling was observed in pancreatic adenocarcinoma cell lines and tumours. However, information on the expression of RelA/p65, the major transcription activating NF-κB sub...
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Article
Cathepsin B-independent abrogation of cell death by CA-074-OMe upstream of lysosomal breakdown
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Chapter
The Role of Lactic Acid in the Mechanism of Neovascularization
It is known that hypoxic tissues generally vascularize. The late professor Michaelson /1948/ was one of the firsts to suppose that his X-factor may be released in hypoxic tissues and since then we have known t...
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Chapter
Hemorrhagic Glaucoma after Intraocular Operations
The causes of rubeosis iridis and hemorrhagic glaucoma are well known. The most frequent are diabetic proliferative retinopathy, central retinal vein occlusion and carotid occlusion. It is also known that in c...