6 Result(s)
within
G Hofstetter
Biomedicine, general
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Article
Open AccessAssociation of gamma-glutamyltransferase with severity of disease at diagnosis and prognosis of ovarian cancer
Gamma-glutamyltransferase (GGT) – a membrane-bound enzyme crucially involved in the cell’s detoxification pathway and apoptotic balance – is involved in tumour development, progression and chemotherapy resista...
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Article
Open AccessDoes thyroid-stimulating hormone influence the prognosis of patients with endometrial cancer? A multicentre trial
Thyroid function has been suggested to interfere with tumour biology and prognosis in different cancers. The present study was performed to investigate the impact of pre-therapeutic serum thyroid-stimulating h...
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Article
Open AccessNomogram prediction for overall survival of patients diagnosed with cervical cancer
Nomograms are predictive tools that are widely used for estimating cancer prognosis. The aim of this study was to develop a nomogram for the prediction of overall survival (OS) in patients diagnosed with cervi...
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Article
Open AccessPrognostic significance of gamma-glutamyltransferase in patients with endometrial cancer: a multi-centre trial
Gamma-glutamyltransferase (GTT), a known marker for apoptotic balance, seems to promote tumour progression, invasion and drug resistance. Recently, high GGT serum levels were shown to be associated with impair...
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Article
Open AccessΔ133p53 is an independent prognostic marker in p53 mutant advanced serous ovarian cancer
We aimed to evaluate the clinical relevance of p53 and p73 isoforms that modulate the function of p53.
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Article
Factors influencing the caffeine test for cytochrome P 448-dependent liver function
Liver function in patients with liver disease can be estimated by caffeine clearance. Our data, however, demonstrate the additional influence of factors other than liver disease on the caffeine test. Smoking e...
