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Article
Distinct downstream targets manifest p53-dependent pathologies in mice
Mdm2, the principal negative regulator of p53, is critical for survival, a fact clearly demonstrated by the p53-dependent death of germline or conditional mice following deletion of Mdm2. On the other hand, Mdm2 ...
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Article
Improved lung function tests on changing from topical timolol: Non-selective beta-blockade impairs lung function tests in elderly patients
Fifty-two elderly glaucomatous patients, without a history of asthma or obstructive airways disease, who were using topical timolol for control of intraocular pressure were recruited. Their topical therapy was...