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  1. Article

    Open Access

    Caspase-3 promotes oncogene-induced malignant transformation via EndoG-dependent Src-STAT3 phosphorylation

    Accumulating evidence suggests that caspase-3 plays critical roles beyond apoptosis, serving pro-survival functions in malignant transformation and tumorigenesis. However, the mechanism of non-apoptotic action...

    Chenchen Zhu, Fushun Fan, Chuan-Yuan Li, Yan **ong, **njian Liu in Cell Death & Disease (2024)

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    Article

    Dual PI3K/HDAC Inhibitor BEBT-908 Exhibits Potent Efficacy as Monotherapy for Primary Central Nervous System Lymphoma

    The efficacy of systemic treatment for primary central nervous system lymphoma (PCNSL) is limited because of the blood–brain barrier (BBB) and the ineffectiveness of chemotherapy. The dual PI3K/HDAC inhibitor ...

    Ning Wang, Zhenxian Mo, Lu Pan, Minhua Zhou, **aolan Ye, **njian Liu… in Targeted Oncology (2023)