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Article
Enhancing (2S)-naringenin production in Saccharomyces cerevisiae by high-throughput screening method based on ARTP mutagenesis
(2S)-Naringenin, a dihydro-flavonoid, serves as a crucial precursor for flavonoid synthesis due to its extensive medicinal values and physiological functions. A pathway for the synthesis of (2S)-naringenin from g...
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Article
Evaluation of genome size and phylogenetic relationships of the Saccharum complex species
“Saccharum complex” is a hypothetical group of species, which is supposed to be involved in the origin of modern sugarcane, and displays large genomes and complex chromosomal alterations. The utilization of restr...
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Article
The draft genome sequence of Scheffersomyces segobiensis strain DSM 27193, a yeast capable of producing palmitoleic acid-rich lipids
In this study, the draft genome of the recently isolated oleaginous yeast Scheffersomyces segobiensis DSM 27193, which can accumulate high content of palmitoleic acid (POA), was sequenced and analyzed. Only few s...
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Article
Modulatory effect of euxanthone in liver cancer-bearing obese mice: crosstalk between PPARγ and TIMP3 signalling axes
Liver cancer is one of the prominent cancer-associated fatal diseases with > 80% of cases befall in low–middle resource nations worldwide. In the current study, we studied the effect of euxanthone (EUX) on obe...
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Article
Genome-wide identification of superoxide dismutase gene families and their expression patterns under low-temperature, salt and osmotic stresses in watermelon and melon
The growth and development of watermelon and melon are affected by abiotic stresses such as cold, salinity and drought. Plant superoxide dismutase (SOD) proteins exerted great effects on plant growth, developm...
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Article
Alternations in the liver metabolome, skin and serum antioxidant function of silver pomfret (Pampus Argenteus) is induced by jellyfish feeding
Many fish species are known to feed on jellyfish. Herein, we observed the effects of jellyfish feeding on silver pomfret using gas chromatography tandem time-of-flight mass spectrometry (GC-TOF–MS) based on me...
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Article
WWP2 and PPP1R3A are abnormally regulated in arrhythmia-induced cardiac damage
The present work aimed to identify the roles of WWP2 (an E3 ubiquitin-protein ligase) and protein phosphatase 1 regulatory subunit 3A (PPP1R3A) in different pathological stages of cardiac arrhythmia developmen...
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Article
Efficacy of chelerythrine against dual-species biofilms of Staphylococcus aureus and Staphylococcus lugdunensis
Staphylococcus aureus and Staphylococcus lugdunensis are often associated with pathogenic biofilms ranging from superficial mucosal to life-threatening systemic infections. Recent studies have reported that chele...
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Article
The complete genome sequence of Bacillus velezensis LPL061, an exopolysaccharide-producing bacterium
Bacillus velezensis LPL061, which shows strong exopolysaccharide (EPS) producing capacity, was isolated from carnations in Bei**g, China. The complete genome of LPL061 comprised a single circular chromosome (3,9...
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Article
Integrated miRNA-seq analysis reveals the molecular mechanism underlying the effect of acupuncture on endometrial receptivity in patients undergoing fertilization: embryo transplantation
Endometrial receptivity (ER) is the main factor affecting in vitro fertilization (IVF) and embryo transplantation. Previous studies have shown that acupuncture might be useful for increasing ER. However, the u...
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Article
The draft genome sequence of Meyerozyma guilliermondii strain YLG18, a yeast capable of producing and tolerating high concentration of 2-phenylethanol
The draft genome of a wild-type Meyerozyma guilliermondii strain YLG18, which could convert l-phenylalanine (l-phe) to 2-phenylethanol (2-PE) and tolerate high concentration of 2-PE was sequenced and analyzed. 18...
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Article
Transcriptomic profiles of human HaCaT cells in response to angelica polysaccharide
The aim of this study was to explore the anti-psoriatic effect and potential mechanism of Angelica polysaccharide (APS) on an in vitro HaCaT cell model. MTS assay was performed to determine whether APS has the...
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Article
Surfactant-modified Aspergillus oryzae lipase as a highly active and enantioselective catalyst for the kinetic resolution of (RS)-1-phenylethanol
The lipase from Aspergillus oryzae was modified with a surfactant and then observed to exhibit high catalytic efficiency and enantioselectivity for the kinetic resolution of (RS)-1-phenylethanol. The influential ...
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Article
Transcriptome-wide analysis of the difference of alternative splicing in susceptible and resistant silkworm strains after BmNPV infection
Novel alternative splicing events were identified from BmNPV-susceptible and -resistant silkworm strains after BmNPV infection using high-throughput RNA-sequencing strategy. In total, 12.82 Gb clean RNA-seq da...
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Article
One-step electrochemically synthesized graphene oxide coated on polypyrrole nanowires as anode for microbial fuel cell
A novel polypyrrole nanowires coated by graphene oxide (PPy-NWs/GO) has been successfully synthesized by one-step electrochemical method, whose structure was different from previously reported PPy/GO composite...
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Article
Comparative genome analysis of Bacillus velezensis reveals a potential for degrading lignocellulosic biomass
Genomes of 24 sequenced Bacillus velezensis strains were characterized to identity shared and unique genes of lignocellulolytic enzymes and predict potential to degrade lignocellulose. All 24 strains had genes th...
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Article
Complete genome sequence of Bacillus velezensis 157 isolated from Eucommia ulmoides with pathogenic bacteria inhibiting and lignocellulolytic enzymes production by SSF
Bacillus velezensis 157 was isolated from the bark of Eucommia ulmoides, and exhibited antagonistic activity against a broad spectrum of pathogenic bacteria and fungi. Moreover, B. velezensis 157 also showed vari...
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Article
Expression, purification and function of cysteine desulfurase from Sulfobacillus acidophilus TPY isolated from deep-sea hydrothermal vent
The cysteine desulfurase (SufS) gene of Sulfobacillus acidophilus TPY, a Gram-positive bacterium isolated from deep-sea hydrothermal vent, was cloned and over-expressed in E. coli BL21. The recombinant SufS prote...
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Article
Biodegradation of pyrene and benzo[a]pyrene in the liquid matrix and soil by a newly identified Raoultella planticola strain
In the current study, the PL7 strain was isolated from soil and identified as Raoultella planticola based on its physiological characteristics and 16S rDNA sequence. By the 10th day, the PL7 strain degraded 52.0%...