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  1. No Access

    Article

    Impact of spinal cord compression from intradural and epidural spinal tumors on perioperative symptoms—implications for surgical decision making

    Spinal cord or cauda equina compression (SCC) is an increasing challenge in clinical oncology due to a higher prevalence of long-term cancer survivors. Our aim was to determine the clinical relevance of SCC re...

    Malte Mohme, Klaus Christian Mende, Theresa Krätzig… in Neurosurgical Review (2017)

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    Article

    Treatment of large thoracic and lumbar paraspinal schwannoma

    Paraspinal neurogenic tumors usually expand into the mediastinum and retroperitoneum and can reach a considerable size before they become symptomatic. Such large tumors are rare. We describe 14 cases of large ...

    Theresa Krätzig, Marc Dreimann, Mark Klingenhöfer, Frank W. Floeth… in Acta Neurochirurgica (2015)

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    Article

    The impact of fluorescence guidance on spinal intradural tumour surgery

    5-Aminolevulinic acid (5-ALA)-based fluorescence-guided surgery was shown to be beneficial for cerebral malignant gliomas. Extension of this technique for resection of meningiomas and cerebral metastasis has b...

    Sven O. Eicker, Frank W. Floeth, Marcel Kamp, Hans-Jakob Steiger… in European Spine Journal (2013)

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    Article

    Local inflammation and devascularization — in vivo mechanisms of the “bystander effect” in VPC-mediated HSV-Tk/GCV gene therapy for human malignant glioma

    Somatic gene therapy with the herpes simplex virus type I thymidine kinase gene/ganciclovir (HSV-Tk/GCV) system and murine retroviral vector producer cells (VPCs) was introduced as a new adjuvant treatment mod...

    Frank W Floeth, Nick Shand, Hans Bojar, Hans B Prisack… in Cancer Gene Therapy (2001)