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  1. No Access

    Chapter and Conference Paper

    A Comparative Study of Suspension Cultivation Systems for the Expansion of Undifferentiated Mouse Embryonic Stem Cells

    Embryonic Stem (ES) cells are self- renewing and pluripotent cells that can differentiate into a variety of cell lineages. Implementation in tissue engineering or as model systems for drug discovery makes ES c...

    Magda Tomala, Sabrina Schmeckebier in Proceedings of the 21st Annual Meeting of … (2012)

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    Chapter and Conference Paper

    A New Variant of the Affinity Matrix Method for Identification of High Producing Cells in Mammalian Cell Culture

    The screening of high-producing cells is a time consuming procedure. Starting from a single cell after a single cell dilution the procedure takes weeks to complete. The affinity matrix method is a technique fo...

    Daniel Landgrebe, Larissa Behr in Proceedings of the 21st Annual Meeting of … (2012)

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    Chapter

    Transcriptome Analysis

    Transcriptome analysis technologies are important systems-biology methods for the investigation and optimization of mammalian cell cultures concerning with regard to growth rates and productivity. For the prod...

    Frank Stahl, Bernd Hitzmann, Kai Mutz in Genomics and Systems Biology of Mammalian … (2012)

  4. Article

    Open Access

    Laser ablation-based one-step generation and bio-functionalization of gold nanoparticles conjugated with aptamers

    Bio-conjugated nanoparticles are important analytical tools with emerging biological and medical applications. In this context, in situ conjugation of nanoparticles with biomolecules via laser ablation in an aque...

    Johanna G Walter, Svea Petersen, Frank Stahl in Journal of Nanobiotechnology (2010)

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    Chapter

    Future Aspects of Bioprocess Monitoring

    Nature has the impressive ability to efficiently and precisely control biological processes by applying highly evolved principles and using minimal space and relatively simple building blocks. The challenge...

    Thomas Becker, Bernd Hitzmann, K. Muffler, Ralf Pörtner in White Biotechnology (2007)