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    Chapter

    Molecular Survival Strategies of Organisms: HSP and Small Molecules for Diagnostics and Drug Development

    Nature has developed evolutionary strategies to synthesize the vast number of what are called secondary metabolites or in short natural products. These include molecules that are able to inhibit heat shock pro...

    Andreas Kirschning, Johanna-Gabriela Walter in Heat Shock Protein-Based Therapies (2015)

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    Chapter and Conference Paper

    A Comparative Study of Suspension Cultivation Systems for the Expansion of Undifferentiated Mouse Embryonic Stem Cells

    Embryonic Stem (ES) cells are self- renewing and pluripotent cells that can differentiate into a variety of cell lineages. Implementation in tissue engineering or as model systems for drug discovery makes ES c...

    Magda Tomala, Sabrina Schmeckebier in Proceedings of the 21st Annual Meeting of … (2012)

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    Chapter and Conference Paper

    A New Variant of the Affinity Matrix Method for Identification of High Producing Cells in Mammalian Cell Culture

    The screening of high-producing cells is a time consuming procedure. Starting from a single cell after a single cell dilution the procedure takes weeks to complete. The affinity matrix method is a technique fo...

    Daniel Landgrebe, Larissa Behr in Proceedings of the 21st Annual Meeting of … (2012)

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    Article

    Isolation of intact RNA from cytometrically sorted Saccharomyces cerevisiae for the analysis of intrapopulation diversity of gene expression

    Characterizing and understanding the functional heterogeneity in a given population on the cellular and molecular level is a great challenge in microbiology. Each microorganism contributes differently to the o...

    Jeannette Achilles, Frank Stahl, Hauke Harms, Susann Müller in Nature Protocols (2007)