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  1. No Access

    Chapter

    Aptazymes: Expanding the Specificity of Natural Catalytic Nucleic Acids by Application of In Vitro Selected Oligonucleotides

    Aptazymes are synthetic molecules composed of an aptamer domain and a catalytic active nucleic acid unit, which may be a ribozyme or a DNAzyme. In these constructs the aptamer domain serves as a molecular swit...

    Johanna-Gabriela Walter, Frank Stahl in Catalytically Active Nucleic Acids (2020)

  2. No Access

    Chapter

    Spezielle labortechnische Reaktoren: Lab-on-a-Chip

    Mikroreaktorsysteme ermöglichen es, auf kleinstem Raum verschiedene Prozessschritte kombiniert ablaufen zu lassen. In diesem Kapitel werden die einzelnen funktionellen Einheiten solcher mikrofluidischen System...

    Janina Bahnemann, Frank Stahl, Thomas Scheper in Handbuch Chemische Reaktoren (2020)

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    Living Reference Work Entry In depth

    Spezielle labortechnische Reaktoren: Lab-on-a-Chip

    Mikroreaktorsysteme ermöglichen es auf kleinstem Raum verschiedene Prozessschritte kombiniert ablaufen zu lassen. In diesem Kapitel werden die einzelnen funktionellen Einheiten solcher mikrofluidischen Systeme...

    Janina Bahnemann, Frank Stahl, Thomas Scheper in Handbuch Chemische Reaktoren

  4. No Access

    Chapter

    Aptamer-Modified Nanoparticles as Biosensors

    Aptamers are short oligonucleotides that are capable of selectively binding to their corresponding target. Therefore, they can be thought of as a nucleic acid-based alternative to antibodies and can substitute...

    Maren Lönne, Guohong Zhu, Frank Stahl… in Biosensors Based on Aptamers and Enzymes (2014)

  5. No Access

    Chapter

    Transcriptome Analysis

    Transcriptome analysis technologies are important systems-biology methods for the investigation and optimization of mammalian cell cultures concerning with regard to growth rates and productivity. For the prod...

    Frank Stahl, Bernd Hitzmann, Kai Mutz… in Genomics and Systems Biology of Mammalian … (2012)

  6. Article

    Open Access

    Laser ablation-based one-step generation and bio-functionalization of gold nanoparticles conjugated with aptamers

    Bio-conjugated nanoparticles are important analytical tools with emerging biological and medical applications. In this context, in situ conjugation of nanoparticles with biomolecules via laser ablation in an aque...

    Johanna G Walter, Svea Petersen, Frank Stahl… in Journal of Nanobiotechnology (2010)

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    Chapter

    Future Aspects of Bioprocess Monitoring

    Nature has the impressive ability to efficiently and precisely control biological processes by applying highly evolved principles and using minimal space and relatively simple building blocks. The challenge...

    Thomas Becker, Bernd Hitzmann, K. Muffler, Ralf Pörtner… in White Biotechnology (2007)