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High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology

Bcl-2 promotes cell survival by inhibiting adapters needed for the activation and cleavage of caspases thus blocking the proteolytic cascade that ultimately dismantles the cell. Bcl-2 has been investigated as ...

Valsamo K Anagnostou, Frank J Lowery, Vassiliki Zolota, Vassiliki Tzelepi… in BMC Cancer (2010)