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  1. No Access

    Article

    Development of a bioartificial liver employing xenogeneic hepatocytes

    Liver failure is a major cause of mortality. A bioartificial liver (BAL) employing isolated hepatocytes can potentially provide temporary support for liver failure patients. We have developed a bioartificial l...

    Wei-Shou Hu, Julie R. Friend, Florence J. Wu, Timothy Sielaff… in Cytotechnology (1997)

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    Article

    A sensitive measurement of oxygen uptake rate using a optochemical sensor

    The measurement of the specific oxygen uptake rate (OUR) of slow growing organisms using a small sample size is often hampered by the consumption of oxygen by the electrode used. Using a optochemical sensor we...

    Chung-Ming Chi, Leah N. Frautschy, Frank B. Cerra, Wei-Shou Hu in Biotechnology Techniques (1993)

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    Article

    Primary culture of rat hepatocytes entrapped in cylindrical collagen gels: An in vitro system with application to the bioartificial liver

    A static culture model employing cylindrical collagen-hepatocyte gels is reported for large scale testing of conditions relevant to the three compartment hollow fiber bioartificial liver. High density hepatocy...

    Scott L. Nyberg, Russell A. Shatford, William D. Payne, Wei-Shou Hu… in Cytotechnology (1992)

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    Article

    Microelectrode measurement of oxygen tensions in collagen-hepatocyte gels

    Microelectrodes have been used for the measurement of oxygen tension in various biological systems.(Silver, 1987) Although not previously reported, microelectrodes allow the direct measurement of oxygen tensio...

    Scott L. Nyberg, Steven M. Santilli, Russell A. Shatford… in Biotechnology Techniques (1991)