14 Result(s)
within
Francesco Scaravilli
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Article
Open AccessA retrospective, Italian multicenter study of complex abdominal wall defect repair with a Permacol biological mesh
Complex abdominal wall defects (CAWDs) can be difficult to repair and using a conventional synthetic mesh is often unsuitable. A biological mesh might offer a solution for CAWD repair, but the clinical outcome...
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Article
Open AccessTranslational evidence for two distinct patterns of neuroaxonal injury in sepsis: a longitudinal, prospective translational study
Brain homeostasis deteriorates in sepsis, giving rise to a mostly reversible sepsis-associated encephalopathy (SAE). Some survivors experience chronic cognitive dysfunction thought to be caused by permanent br...
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Article
Gene Expression Profile in Rat Dorsal Root Ganglion Following Sciatic Nerve Injury and Systemic Neurotrophin-3 Administration
Following sciatic nerve transection in adult rats, a proportion of injured dorsal root ganglion (DRG) neurons die, through apoptosis, over the following 6 months. Previous studies showed that axotomy and neuro...
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Article
Open AccessTrisomy 19 ependymoma, a newly recognized genetico-histological association, including clear cell ependymoma
Ependymal tumors constitute a clinicopathologically heterogeneous group of brain tumors. They vary in regard to their age at first symptom, localization, morphology and prognosis. Genetic data also suggests he...
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Article
Cerebral CD8+ lymphocytosis in HIV-1 infected patients with immune restoration induced by HAART
In HIV infected persons, highly active antiretroviral therapy (HAART) has reduced both the morbidity and incidence of several disorders. Its effects on direct HIV-induced damage to the CNS remain controversial...
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Article
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
Huntington disease is one of nine inherited neurodegenerative disorders caused by a polyglutamine tract expansion. Expanded polyglutamine proteins accumulate abnormally in intracellular aggregates. Here we sho...
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Article
Detection of infectious agents in brain of patients with acute hemorrhagic leukoencephalitis
Acute hemorrhagic leukoencephalitis (AHL) is a rare and usually fatal disorder characterized clinically by an acute onset of neurologic abnormalities. It may occur in association with a viral illness or vaccin...
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Article
Central pontine myelinolysis in AIDS
Central pontine myelinolysis (CPM) is an uncommon complication in sick patients with severe underlying disorders such as chronic alcoholism, malignancy, malnutrition and hyponatraemia. We report two patients ...
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Article
Familial Lafora body disease of late onset: report of four cases in one family and a review of the literature
Lafora body disease is one cause of progressive myoclonus epilepsy. It typically presents in the second decade with generalized seizures, myoclonus and then intellectual decline. Death is usual within 10 year...
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Article
Sciatic nerve injury in the adult rat: comparison of effects on oligosaccharide, CGRP and GAP43 immunoreactivity in primary afferents following two types of trauma
Using immunocytochemical and morphometric techniques, the localisation of three neuronal oligosaccharide antigens (two lactoseries and one globoseries oligosaccharide) were studied in the spinal cord and dorsa...
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Article
An immunohistochemical study of p53 and proliferating cell nuclear antigen expression in progressive multifocal leukoencephalopathy
Nuclear p53 immunoreactivity is demonstrated in infected oligodendroglia, as well as in a proportion of reactive and bizarre astrocytes, in seven progressive multifocal leukoencephalopathy (PML) biopsies. This...
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Article
PCR detection of HIV proviral DNA in the brain of an asymptomatic HIV-positive patient
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Article
Reduced numbers of calcitonin gene-related peptide-(CGRP-) and tachykinin-immunoreactive sensory neurones associated with greater enkephalin immunoreactivity in the dorsal horn of a mutant rat with hereditary sensory neuropathy
The mutilated foot rat is a mutant with autosomal recessive sensory neuropathy and frequent mutilation of the hindlimbs. Decreased numbers of dorsal root ganglion cells and diminished sensitivity to painful st...
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Article
Enzyme replacement in grafted nerve of twitcher mouse
‘Twitcher’ is a recently recognized mouse mutant which, on the basis of morphological1 and enzymatic2 criteria, represents a murine model for globoid-cell leukodystrophy in man3. In the twitcher mouse, myelin she...
