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  1. Article

    Open Access

    Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma

    The outcome of patients affected by high-risk or metastatic neuroblastoma (NB) remains grim, with ≥ 50% of the children experiencing relapse or progression of the disease despite multimodal, intensive treatmen...

    Nicola Tumino, Gerrit Weber, Francesca Besi… in Journal of Hematology & Oncology (2021)

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  2. No Access

    Article

    Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting

    Daratumumab (Dara), a multiple myeloma (MM) therapy, is an antibody against the surface receptor CD38, which is expressed not only on plasma cells but also on NK cells and monocytes. Correlative data have high...

    Domenico Viola, Ada Dona, Enrico Caserta, Estelle Troadec, Francesca Besi… in Leukemia (2021)

  3. Article

    Open Access

    PMN-MDSC are a new target to rescue graft-versus-leukemia activity of NK cells in haplo-HSC transplantation

    Nicola Tumino, Francesca Besi, Anna Laura Di Pace, Francesca Romana Mariotti… in Leukemia (2020)

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