10 Result(s)
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Chapter
Human Evolution: The Genomic Evidence
Since Darwin, we understand the process that generates biological diversity, including human diversity, as a genealogical tree that relates all individuals and all species. Within this framework of analysis, a...
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Chapter
The Y Chromosome
Most of the length of the Y chromosome escapes recombination with the X chromosome and is strictly paternally inherited. This has profound evolutionary implications and provides (together with the matrilineal ...
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Chapter
Africa
The higher genetic diversity present in African human groups is the result of our African origin and the subsequent bottleneck that took place during the colonization of the rest of the continents. However, th...
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Chapter
The Parallel Lives of Human Y Chromosome Lineages Across the Strait of Gibraltar
The patrilineal transmission of the Y chromosome and the fact that diversity in it accumulates along a strict genealogy imply that, by observing the current Y chromosome diversity in men, inferences can be mad...
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Article
Open AccessGenetic adaptation of the antibacterial human innate immunity network
Pathogens have represented an important selective force during the adaptation of modern human populations to changing social and other environmental conditions. The evolution of the immune system has therefore...
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Article
Open AccessAfrican signatures of recent positive selection in human FOXI1
The human FOXI1 gene codes for a transcription factor involved in the physiology of the inner ear, testis, and kidney. Using three interspecies comparisons, it has been suggested that this may be a gene under hum...
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Article
Open AccessGenetic origin, admixture, and asymmetry in maternal and paternal human lineages in Cuba
Before the arrival of Europeans to Cuba, the island was inhabited by two Native American groups, the Tainos and the Ciboneys. Most of the present archaeological, linguistic and ancient DNA evidence indicates a...
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Article
Comparative Genetics of Functional Trinucleotide Tandem Repeats in Humans and Apes
Several human neurodegenerative disorders are caused by the expansion of polymorphic trinucleotide repeat regions. Many of these loci are functional short tandem repeats (STRs) located in brain-expressed genes...
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Article
A Recent Shift from Polygyny to Monogamy in Humans Is Suggested by the Analysis of Worldwide Y-Chromosome Diversity
Molecular genetic data contain information on the history of populations. Evidence of prehistoric demographic expansions has been detected in the mitochondrial diversity of most human populations and in a Y-ch...
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Article
Population Genetics of Y-Chromosome Short Tandem Repeats in Humans
Eight human short tandem repeat polymorphisms (STRs) also known as microsatellites—DYS19, DYS388, DYS390, DYS391, DYS392, DYS393, DYS389I, and DYS389II, map** in the Y chromosome—were analyzed in two Iberia...
