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Article
Open AccessInfluence of circadian clocks on adaptive immunity and vaccination responses
The adaptive immune response is under circadian control, yet, why adaptive immune reactions continue to exhibit circadian changes over long periods of time is unknown. Using a combination of experimental and m...
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Protocol
Recording of Diurnal Gene Expression in Peripheral Organs of Mice Using the RT-Biolumicorder
There is high interest in investigating the daily dynamics of gene expression in mammalian organs, for example, in liver. Such studies help to elucidate how and with what kinetics peripheral clocks integrate c...
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Article
Open AccessCircadian clocks guide dendritic cells into skin lymphatics
Migration of leukocytes from the skin to lymph nodes (LNs) via afferent lymphatic vessels (LVs) is pivotal for adaptive immune responses1,2. Circadian rhythms have emerged as important regulators of leukocyte tra...
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Article
Cellular circadian period length inversely correlates with HbA1c levels in individuals with type 2 diabetes
The circadian system plays an essential role in regulating the timing of human metabolism. Indeed, circadian misalignment is strongly associated with high rates of metabolic disorders. The properties of the ci...
