5 Result(s)
within
Flavie Lavoie-Cardinal
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Article
Open AccessResolution enhancement with a task-assisted GAN to guide optical nanoscopy image analysis and acquisition
Super-resolution fluorescence microscopy methods enable the characterization of nanostructures in living and fixed biological tissues. However, they require the adjustment of multiple imaging parameters while ...
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Article
Open AccessA postzygotic de novo NCDN mutation identified in a sporadic FTLD patient results in neurochondrin haploinsufficiency and altered FUS granule dynamics
Frontotemporal dementia (FTD) is a heterogeneous clinical disorder characterized by progressive abnormalities in behavior, executive functions, personality, language and/or motricity. A neuropathological subty...
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Article
Open AccessNeuronal activity remodels the F-actin based submembrane lattice in dendrites but not axons of hippocampal neurons
The nanoscale organization of the F-actin cytoskeleton in neurons comprises membrane-associated periodical rings, bundles, and longitudinal fibers. The F-actin rings have been observed predominantly in axons b...
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Article
Open AccessA machine learning approach for online automated optimization of super-resolution optical microscopy
Traditional approaches for finding well-performing parameterizations of complex imaging systems, such as super-resolution microscopes rely on an extensive exploration phase over the illumination and acquisitio...
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Article
Open AccessGold nanoparticle-assisted all optical localized stimulation and monitoring of Ca2+ signaling in neurons
Light-assisted manipulation of cells to control membrane activity or intracellular signaling has become a major avenue in life sciences. However, the ability to perform subcellular light stimulation to investi...
