6 Result(s)
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Article
Open AccessA comprehensive method for amplicon-based and metagenomic characterization of viruses, bacteria, and eukaryotes in freshwater samples
Studies of environmental microbiota typically target only specific groups of microorganisms, with most focusing on bacteria through taxonomic classification of 16S rRNA gene sequences. For a more holistic unde...
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Article
Open AccessEvaluation of shotgun metagenomics sequence classification methods using in silico and in vitro simulated communities
The field of metagenomics (study of genetic material recovered directly from an environment) has grown rapidly, with many bioinformatics analysis methods being developed. To ensure appropriate use of such meth...
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Chapter
Computational Prediction of Protein Subcellular Localization, Genomic Islands, and Virulence to Aid Antigen Discovery
Subunits of bacterial proteins involved in virulence, as well as bacterial cell surface and secreted proteins, may be prioritized as potential vaccine components warranting further study. Computational predict...
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Article
Protein interaction data curation: the International Molecular Exchange (IMEx) consortium
Presented is an update on the status and current practices of the International Molecular Exchange (IMEx) consortium and on its efforts to create a single nonredundant set of protein interactions curated from ...
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Article
PSICQUIC and PSISCORE: accessing and scoring molecular interactions
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Chapter
Systems-Level Analyses of the Mammalian Innate Immune Response
The regulation of the innate immune response, our first line of defence against infectious disease, does not involve simple linear pathways but rather complex inter-connected networks of interactions, regulato...
