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Open AccessDoubts and concerns about COVID-19 uncertainties on imaging data, clinical score, and outcomes
COVID-19 is a pandemic disease affecting predominantly the respiratory apparatus with clinical manifestations ranging from asymptomatic to respiratory failure. Chest CT is a crucial tool in diagnosing and eval...
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Open AccessReal-world use of remdesivir for the treatment of patients admitted to Italian hospitals with COVID-19: the nationwide retrospective FADOI-RECOVER study
Remdesivir is widely used for treatment of SARS-CoV-2 pneumonia. The aim of this study was to evaluate the characteristics of patients with moderate-to-severe COVID-19 treated with remdesivir, and their outcom...
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Open AccessCharacteristics of COVID-19 vaccinated and unvaccinated patients admitted to Careggi University Hospital, Florence, Italy
More than 11.5 billion COVID-19 vaccine doses have been administered around the world. Although vaccine effectiveness for severe infections is reported to be 89.0%, breakthrough infections are common and may l...
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Open AccessRole of prognostic scores in predicting in-hospital mortality and failure of non-invasive ventilation in adults with COVID-19
We tested the prognostic performance of different scores for the identification of subjects with acute respiratory failure by COVID-19, at risk of in-hospital mortality and NIV failure. We conducted a retrospe...
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“Smoke on the water”: a challenging case of pneumonia
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Open AccessCompassionate use of JAK1/2 inhibitor ruxolitinib for severe COVID-19: a prospective observational study
Overwhelming inflammatory reactions contribute to respiratory distress in patients with COVID-19. Ruxolitinib is a JAK1/JAK2 inhibitor with potent anti-inflammatory properties. We report on a prospective, obse...
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The doctor who stared at schistocytes: an intriguing case of suspected thrombotic microangiopathic anemia
A 33-year-old man with type 1 diabetes mellitus was admitted to the Internal Medicine Unit due to subacute onset of exertional dyspnea, with evidence at initial blood exams of severe macrocytic anemia with thr...
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Open AccessCorrection to: Acute cardiovascular events in patients with community acquired pneumonia: results from the observational prospective FADOI-ICECAP study
An amendment to this paper has been published and can be accessed via the original article.
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Open AccessAcute cardiovascular events in patients with community acquired pneumonia: results from the observational prospective FADOI-ICECAP study
The burden of cardiovascular (CV) complications in patients hospitalised for community-acquired pneumonia (CAP) is still uncertain. Available studies used different designs and different criteria to define CV ...
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COVID-19 pandemic and Internal Medicine Units in Italy: a precious effort on the front line
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Personalized machine learning approach to predict candidemia in medical wards
Candidemia is a highly lethal infection; several scores have been developed to assist the diagnosis process and recently different models have been proposed. Aim of this work was to assess predictive performan...
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Risk factors and outcomes of new-onset atrial fibrillation in patients hospitalized in an internal medicine ward: a case–control study
Atrial fibrillation (AF) is a frequent pathology in Internal Medicine departments. The aim of our study was to identify the risk factors associated with the development of new-onset AF during hospitalization a...
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A prediction rule for early recognition of patients with candidemia in Internal Medicine: results from an Italian, multicentric, case–control study
Increasing prevalence of candidemia in Internal Medicine wards (IMWs) has been reported in recent years, but risk factors for candida bloodstream infection in patients admitted to IMW may differ from those kno...
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Performance status and in-hospital mortality of elderly patients with community acquired pneumonia
To evaluate the role of performance status evaluated by the Eastern Cooperative Oncology Group (ECOG) score in predicting 30-day mortality in subjects hospitalized for community acquired pneumonia (CAP), this ...
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Independent risk factors for mortality in critically ill patients with candidemia on Italian Internal Medicine Wards
Candida is an increasing cause of bloodstream infection and is associated with significant morbidity and mortality. The aim of our study is to analyze risk factors for short-term mortality in patients with blo...
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Every cloud has a silver lining
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Usefulness of procalcitonin in differentiating Candida and bacterial blood stream infections in critically ill septic patients outside the intensive care unit
We aimed to explore the role of procalcitonin (PCT) for the diagnosis of Candida spp. bloodstream infections in a population of critically ill septic patients admitted to internal medicine units. This is a retros...
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The classification of hospitalized patients with hyperglycemia and its implication on outcome: results from a prospective observational study in Internal Medicine
The relevance of classifying hyperglycemic hospitalized subjects (HS) as known diabetes (D), newly discovered diabetes (ND), and stress hyperglycemia (SH) is unclear. The aim of this study was to determine the...
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Simplified PESI score and sex difference in prognosis of acute pulmonary embolism: a brief report from a real life study
Prognostic stratification of acute pulmonary embolism (PE) remains a challenge in clinical practice. Simplified PESI (sPESI) score is a practical validated score aimed to stratify 30-day mortality risk in acut...
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Septic shock from community-onset pneumonia: is there a role for aspirin plus macrolides combination?
