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Article
Primary Management of Operable Locally Advanced Oral Cavity Squamous Cell Carcinoma: Current Concepts and Strategies
Locally advanced oral cavity carcinoma (LAOCSCC) is primarily treated with surgery followed by radiotherapy with or without chemotherapy.
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Article
Poorly differentiated thyroid carcinomas: conceptual controversy and clinical impact
Poorly differentiated thyroid carcinomas (PDTC) are rare diseases; nevertheless, they account for the majority of deaths from non-anaplastic follicular cell-derived thyroid carcinomas. Establishing the diagnos...
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Article
Experimental Models of Sinonasal Tumors for Preclinical Testing of Candidate Targeted Therapies
This paper aims to describe the available in vitro and in vivo models of different sinonasal cancer subtypes as tools both for improving our knowledge of the signaling pathways involved in tumorigenesis and fo...
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Article
Open AccessCorrection to: Pharyngeal Reconstruction Methods to Reduce the Risk of Pharyngocutaneous Fistula After Primary Total Laryngectomy: A Sco** Review
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Open AccessPharyngeal Reconstruction Methods to Reduce the Risk of Pharyngocutaneous Fistula After Primary Total Laryngectomy: A Sco** Review
The most common early postoperative complication after total laryngectomy (TL) is pharyngocutaneous fistula (PCF). Rates of PCF are higher in patients who undergo salvage TL compared with primary TL. Published...
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Article
Open AccessOncological and functional outcomes of transoral laser surgery for hypopharyngeal carcinoma
Surgical resection or radiotherapy (RT) are standard approaches for early-staged hypopharyngeal squamous cell carcinoma (HPSCC). Transoral laser microsurgery (TOLMS) seems to provide good oncological and funct...
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Article
Complications related to the Cook–Swartz implantable Doppler probe use in head and neck microvascular reconstruction: a systematic review
Vascular perfusion research has been dedicated to identify inexpensive, effective, and easy to use methods to assess free flap perfusion for both buried and non-buried flaps.
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Article
Benign Peripheral Non-cranial Nerve Sheath Tumors of the Neck
Benign peripheral non-cranial nerve sheath tumors are rare lesions, including both schwannomas and neurofibromas. These tumors arise from Schwann cells, and may originate from any peripheral, cranial, or auton...
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Article
Open AccessThe Selective Role of Open and Endoscopic Approaches for Sinonasal Malignant Tumours
Endoscopic endonasal surgery has been demonstrated to be effective in the treatment of selected cases of sinonasal cancers. However, in cases of locally advanced neoplasms, as well as recurrences, the most app...
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Article
Open AccessManaging Cachexia in Head and Neck Cancer: a Systematic Sco** Review
Patients with head and neck cancer (HNC) are usually confronted with functional changes due to the malignancy itself or its treatment. These factors typically affect important structures involved in speech, br...
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Article
Asymptomatic swallowing disorders may be present in individuals with laryngeal and hypopharyngeal cancer treated with chemo-radiotherapy
Patients with advanced laryngeal and hypopharyngeal cancer are often treated with chemo-radiotherapy to avoid total laryngectomy. Subclinical swallowing disorders could be present in these patients even though...
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The Importance of Frontal Sinus Surgery in Craniofacial Resection. Endoscopic, Open, and Combined Approaches
Craniofacial approaches are designed to safely remove the area between the roof of the paranasal sinuses/nasal fossa and the base of the anterior fossa, that is, the upper part of the ethmoids, the planum sphe...
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Article
Minimally invasive video-assisted parathyroidectomy (MIVAP) without intraoperative PTH determination
Minimally invasive video-assisted parathyroidectomy (MIVAP) has become a standard approach to primary hyperparathyroidism (pHPT) since described. Although intraoperative parathyroid hormone assay (IOPTH) has b...
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Article
Standardization for oncologic head and neck surgery
The inherent variability in performing specific surgical procedures for head and neck cancer remains a barrier for accurately assessing treatment outcomes, particularly in clinical trials. While non-surgical m...
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Article
The presence of dysphagia in patients with cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS): a subjective and objective study
The aim of this study was to determine the prevalence of dysphagia in patients with cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS), characterizing this condition, both in its objectiv...
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Article
Open AccessNext-generation sequencing for identification of actionable gene mutations in intestinal-type sinonasal adenocarcinoma
Intestinal-type sinonasal adenocarcinoma (ITAC) is a rare tumor carrying poor prognosis and needing new treatment options. The aim of this study was to identify actionable gene mutations that can guide new per...
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Article
Oncological and functional outcomes of transoral laser surgery for laryngeal carcinoma
Transoral laser microsurgery (TLM) has become the standard approach for treatment of early-stage laryngeal carcinoma in most institutions due to their good oncological and functional results with few local com...
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Article
Radiation-induced carotid artery lesions
To review the current aspects of knowledge related to the risk of cerebrovascular events in patients receiving head and neck radiotherapy.
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Article
Molecular markers in well-differentiated thyroid cancer
Thyroid nodules are of common occurrence in the general population. About a fourth of these nodules are indeterminate on aspiration cytology placing many a patient at risk of unwanted surgery. The purpose of t...
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Article
Open AccessConcurrent and orthogonal gold(I) and ruthenium(II) catalysis inside living cells
The viability of building artificial metabolic pathways within a cell will depend on our ability to design biocompatible and orthogonal catalysts capable of achieving non-natural transformations. In this conte...
