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Chapter and Conference Paper
Design Methodologies for Sustainable Products from Mixed Waste Plastics and Foundry Sands
This design research proposes, through cooperation between the private sector (industry) and the public sector (university), new furniture and cladding solutions to integrate the urban environment. It seeks to...
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Article
Open Access“I have always lived with the disease in the family”: family adaptation to hereditary cancer-risk
Hereditary cancer syndromes have been conceptualized as a family level process. The present study explores the complexity and challenges of family adaptation to the hereditary cancer syndrome, in the context o...
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Chapter and Conference Paper
Maximizing the Efficiency of By-Product Treatment by Multi-metal Recovery and Slag Valorization
Complete utilization of every material mined seems to be a highly obvious strategy to save natural resources and avoid residues to be dumped. In fact, examples where this is practiced are very limited. Often r...
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Article
Alkali-Activated Cements from Urban, Mining and Agro-Industrial Waste: State-of-the-art and Opportunities
Facing the beginning of the third decade of the twenty-first century, humanity faces an environmental threat that can pose some serious concerns regarding the life on the planet as we know it. The industrial s...
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Article
Open AccessOverexpression of circulating MiR-30b-5p identifies advanced breast cancer
Breast cancer (BrC) remains the leading cause of cancer-related death in women, mainly due to recurrent and/or metastatic events, entailing the need for biomarkers predictive of progression to advanced disease...
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Chapter
Environmental Factors and Their Influence on Intestinal Fibrosis
Multiple endogenous and exogenous factors have been implicated in the development of inflammatory bowel disease (IBD), comprising Crohn’s disease and ulcerative colitis; these factors may initiate and maintain...
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Chapter and Conference Paper
An OS-Oriented Performance Monitoring Tool for Multicore Systems
Hardware performance monitoring counters (PMCs) have proven effective in characterizing application performance. Because PMCs can be only accessed directly at the OS privilege level, kernel-level tools must be...
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Chapter and Conference Paper
Exploring the Throughput-Fairness Trade-off on Asymmetric Multicore Systems
Symmetric-ISA (instruction set architecture) asymmetric-performance multicore processors (AMPs) were shown to deliver higher performance per watt and area than symmetric CMPs (Chip Multi-Processors). Previous ...
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Article
Detection of Colorectal Neoplasia by Colonoscopy in Average-Risk Patients Age 40–49 Versus 50–59 Years
The USPSTF recommends beginning colorectal cancer screening at age 50. A recent study showed prevalence of colorectal adenomas among individuals aged 40–49 was similar to that among those aged 50–59.
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Chapter
Ancient Clay Bricks: Manufacture and Properties
Clay brick masonry is one of the oldest and most durable construction techniques used by mankind. Masonry consists of manually built stable stacks of small elements, with or without mortar. It was a fundamenta...
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Article
Haplotype and quantitative transcript analyses of Portuguese breast/ovarian cancer families with the BRCA1 R71G founder mutation of Galician origin
We investigated the functional effect of the missense variant c.211A>G (R71G) localized at position -2 of exon 5 donor splice site in the BRCA1 gene and evaluated whether Portuguese and Galician families with thi...
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Article
The c.156_157insAlu BRCA2 rearrangement accounts for more than one-fourth of deleterious BRCA mutations in northern/central Portugal
We evaluated the contribution of an Alu insertion in BRCA2 exon 3 (c.156_157insAlu) to inherited predisposition to breast/ovarian cancer in 208 families originated mostly from northern/central Portugal. We identi...
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Chapter and Conference Paper
A Power-Efficient and Scalable Load-Store Queue Design
The load-store queue (LQ-SQ) of modern superscalar processors is responsible for kee** the order of memory operations. As the performance gap between processing speed and memory access becomes worse, the cap...