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Article
Mechanism of X-ray Inhibition of the Sodium Pump in Human Erythrocytes: Adenotriphosphatase Activity of Stromata
PREVIOUS results have shown that X-irradiation of human erythrocytes decreases the active efflux of sodium (sodium pump)1. However, 890 rads and 4,450 rads, which are effective in inducing a 45 and 73 per cent de...
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Article
Control of Degradation and Synthesis of Induced Tyrosine Aminotransferase studied in Hepatoma Cells in Culture
WE have been studying the mechanism of tyrosine amino-transferase (TAT) induction by adrenal steroids in hepatoma (HTC) cell cultures1,2. The hormones increase the rate of enzyme synthesis resulting in an increas...
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Chapter
Phosphorylation of Estradiol Receptor on Tyrosine and Interaction of Estradiol and Glucocorticoid Receptors with Antiphosphotyrosine Antibodies
Phosphorylation of proteins on tyrosine is a recent finding; it is a rare event and seems to be related to growth factor induced cell multiplication, cell transformation(1) and to cell differentiation(2). Seve...
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Article
Eigenstresses in Anisotropic Films
A closed-form solution for a macroscopically homogeneous, fully anisotropie layer subject to non-uniform through-thickness eigenstrain is presented, and employed in determining the three-dimensional deformatio...
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Chapter
An Effective Plate Element for Contact Problems
In the present work the attention is devoted to unilateral frictionless contact problems within the class of flat structures. We show that the use of inappropriate plate elements, such as the displacement-base...
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Chapter
Interactions of Estrogen Receptors with Signal Cascade Molecules
Estradiol activates Src and a canonical Src-dependent pathway including Shc/Ras and Erks in human mammary cancer-derived MCF-7 cells(1). In addition, it immediately and transiently stimulates Yes, another ubiquit...
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Chapter
Numerical Algorithm for a Three-dimensional Stress-induced Solid-phase-transformation Model
This work focuses on a three-dimensional thermomechanical model, recently proposed by Souza et al. [4] for stress-induced solid phase transformations and able to reproduce the main features of shape-memory mat...
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Article
Stainless and shape memory alloy coronary stents: a computational study on the interaction with the vascular wall
Balloon-expandable and self-expandable stents are the two types of coronary stents available. Basically, they differ in the modality of expansion.
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Chapter
A Finite Element for the Analysis of Monoclinic Laminated Plates
This paper presents a 4-node finite element, based on a First-order Shear-Deformation Theory (FSDT), for the analysis of composite monoclinic laminated plates. A mixed-enhanced variational formulation is adopt...
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Chapter
A Mixed FSDT Finite-Element Formulation for the Analysis of Composite Laminates Without Shear Correction Factors
A new 4-node finite element for the analysis of laminated plates is developed starting from a partial-mixed FSDT variational formulation, which considers out-of-plane shear stresses as primary variables. It do...
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Chapter and Conference Paper
Toward an exhaustive modeling of the macroscopic behaviour of shape memory alloys
The employment of shape memory alloys (SMA) in a large number of applications in the fields of aeronautical, biomedical and structural engineering constitutes the basis for an increasing interest of researcher...
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Chapter and Conference Paper
Numerical Testing on Return Map Algorithms for von-Mises Plasticity with Nonlinear Hardening based on a Generalized Midpoint Integration Scheme
We consider an associative von-Mises elastoplastic constitutive model in the realm of small deformations [1]. The model takes into account both linear isotropic hardening and linear/nonlinear kinematic hardening....
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Article
SMA Numerical Modeling Versus Experimental Results: Parameter Identification and Model Prediction Capabilities
In this work, we briefly review the one-dimensional version of a well-known phenomenological shape memory alloy (SMA) constitutive model able to represent the main macroscopic SMA macroscopic behaviors (i.e., ...
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Article
Nitinol Embolic Protection Filters: Design Investigation by Finite Element Analysis
The widespread acceptance of carotid artery stenting (CAS) to treat carotid artery stenosis and its effectiveness compared with surgical counterpart, carotid endarterectomy (CEA), is still a matter of debate. ...
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Chapter
Non-Genomic Action of Sex Steroid Hormones
This chapter aims at giving a concise, up-to-date view of the non-genomic action of sex-steroid hormones and some related aspects. It includes an overview of the identity of the receptors mediating non-genomic...
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Chapter
A Beam Finite Element for Nonlinear Analysis of Shape Memory Alloy Devices
A large displacement finite rotation beam finite element formulation for shape memory alloy structural analysis is proposed. The Reissner-Mindlin beam model is considered in the total Lagrangian form. A refere...
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Article
Steroid signaling activation and intracellular localization of sex steroid receptors
In addition to stimulating gene transcription, sex steroids trigger rapid, non-genomic responses in the extra-nuclear compartment of target cells. These events take place within seconds or minutes after hormon...
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Chapter and Conference Paper
Shape Memory Alloys: Material Modeling and Device Finite Element Simulations
The use of shape memory alloys (SMA) in an increasing number of applications in many fields of engineering, and in particular in biomedical engineering, is leading to a growing interest toward an exhaustive mo...
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Protocol
Analysis of Androgen Receptor Rapid Actions in Cellular Signaling Pathways: Receptor/Src Association
Much evidence indicates that, with few exceptions, non-genomic actions of steroids are mediated by receptors universally known as nuclear receptors. Steroid receptors do not exhibit intrinsic tyrosine kinase a...
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Article
Theoretical and Experimental Study of the Shape Memory Effect of Beams in Bending Conditions
In this study, the shape memory effect of SMA beams under complex stress conditions is studied by means of a finite element model. The 1D version of a well-established SMA constitutive model is utilized in the...