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  1. No Access

    Article

    Histone modification landscape and the key significance of H3K27me3 in myocardial ischaemia/reperfusion injury

    Histone modifications play crucial roles in the pathogenesis of myocardial ischaemia/reperfusion (I/R) injury. However, a genome-wide map of histone modifications and the underlying epigenetic signatures in my...

    Le Ni, Bowen Lin, Yan** Zhang, Lingjie Hu, Jianghua Lin… in Science China Life Sciences (2023)

  2. Article

    Open Access

    PKM2 deficiency exacerbates gram-negative sepsis-induced cardiomyopathy via disrupting cardiac calcium homeostasis

    Sepsis is a life-threatening syndrome with multi-organ dysfunction in critical care medicine. With the occurrence of sepsis-induced cardiomyopathy (SIC), characterized by reduced ventricular contractility, the...

    Le Ni, Bowen Lin, Meiting Shen, Can Li, Lingjie Hu, Fengmei Fu… in Cell Death Discovery (2022)

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