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  1. No Access

    Article

    Immunoaffinity Nanoprobe-Based MALDI-TOF MS for Detection of Fragments of N-Telopeptides of Type I Collagen

    Osteoporosis is one of the major bone-related diseases. Among the biomarkers of bone resorption, type I collagen cross-linked N-telopeptides (NTx) are terminal metabolites specifically derived from the degrada...

    Yu-Cheng Hsiao, Ming-Hsuan Chang in International Journal of Peptide Research … (2014)

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    Article

    Design, synthesis, and evaluation of fluorescent cell-penetrating peptidic antagonists of Grb2-SH2 for targeting MCF-7 breast cancer cells

    The growth factor receptor-bound protein-Src homology 2 (Grb2-SH2) domain plays an important role in the oncogenic Ras signaling pathway, which is involved in cell proliferation and differentiation. We focused...

    Yu-Cheng Hsiao, Chen-Yu Lee, Yi-Jhen Lin, Shu-Huai Tsai in Medicinal Chemistry Research (2013)

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    Chapter and Conference Paper

    Surface Plasmon Resonance- and Quartz Crystal Microbalance-based Methods for Detecting GRB2 SH2 / Peptide Interaction

    Feng-Di T. Lung, Wan Ching Li, Chien-Chung Liou in Understanding Biology Using Peptides (2006)

  4. No Access

    Chapter

    Structure/activity studies of peptide library-based integrase inhibitors

    Feng-Di T. Lung, Ya-Qiu Long, Nouri Neamati in Peptides for the New Millennium (2002)

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    Chapter

    High affinity nonphosphorylated cyclic peptide inhibitors of Grb2-SH2/growth factor receptor interactions

    Ya-Qiu Long, Feng-Di T. Lung, Johannes H. Voigt in Peptides for the New Millennium (2002)

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    Chapter

    Novel non-phosphorylated peptides binding to the Grb2-SH2 domain

    Feng-Di T. Lung, Lakshmi Sastry, Shaomeng Wang in Peptides Frontiers of Peptide Science (2002)

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    Chapter

    Functional site studies with peptide segments of Cdk inhibitory proteins

    Peter P. Roller, Feng-Di T. Lung, Masato Mutoh in Peptides Frontiers of Peptide Science (2002)

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    Chapter

    NMR based solution structure and dynamics of a nonphosphorylated cyclic peptide inhibitor for the Grb2 SH2 domain

    Feng-Di T. Lung, Ming-Tao Pai, Yuan-Chou Lou in Peptides for the New Millennium (2002)

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    Chapter

    Stability and Peptide Binding Specificity of BTK SH2 Domain: Molecular Basis for X-Linked Agammaglobulinemia

    X-Linked agammaglobulinemia (XLA), an inherited disease, is caused by mutations in the Bruton’s tyrosine kinase (BTK) [1]. Like many other cytoplasmic tyrosine kinases in signaling pathways, BTK contains an N-...

    Shiou-Ru Tzeng, Ming-Tao Pai, Feng-Di T. Lung in Peptides: The Wave of the Future (2001)

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    Chapter

    Epitope Map** of Anti-Type I Collagen Crosslinked N-Telopeptide Antibody with Synthetic Peptides

    Osteoporosis is a disease characterized by low bone mass and by architectural deterioration of bone tissue, two factors related to abnormalities of bone turnover [1,2]. This disease influences the health of me...

    Huey-Yi Chen, Yen-Meng Liou, Chiu-Heng Chen in Peptides: The Wave of the Future (2001)

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    Chapter

    Structure-Based Design, Synthesis, and Surface Plasmon Resonance (SPR) Detection of Antagonists of the Grb2 SH2 Domain

    One of the critical intracellular signal transduction pathway involves the binding of Grb2 SH2 domain to the phosphotyrosine (pTyr) motifs on growth factors such as EGFR and erbB2, leading to downstream activa...

    Feng-Di T. Lung, Jia-Yin Tsai, Shu-Yie Wei in Peptides: The Wave of the Future (2001)

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    Article

    Development of non-phosphorylated cyclic thioether peptide binding to the Grb2-SH2 domain

    One of the critical intracellular signaling pathways involves specific interactions between growth factor receptors and the adaptor protein Grb2. These interactions normally involve specific tyrosine phosphory...

    Feng-Di T. Lung, C. Richter King, Peter P. Roller in Letters in Peptide Science (1999)

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    Article

    Development of non-phosphorylated cyclic thioether peptide binding to the Grb2-SH2 domain

    One of the critical intracellular signaling pathways involves specific interactions between growth factor receptors and the adaptor protein Grb2. These interactions normally involve specific tyrosine phosphory...

    Feng-Di T. Lung, C. Richter King, Peter P. Roller in Letters in Peptide Science (1999)