4 Result(s)
within
Feng Jiang**
Biomedicine
English
Cancer Research
Immunology
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Article
Open AccessPiperlongumine conquers temozolomide chemoradiotherapy resistance to achieve immune cure in refractory glioblastoma via boosting oxidative stress-inflamation-CD8+-T cell immunity
The failure of novel therapies effective in preclinical animal models largely reflects the fact that current models do not really mimic the pathological/therapeutic features of glioblastoma (GBM), in which the...
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Article
The Development and Application of Virtual Reality Animation Simulation Technology: Take Gastroscopy Simulation System as an Example
Virtual reality (VR) technology has a great potential in the field of medical simulation due to its immersion, interactivity and autonomy. It provides a new direction for integration and application in various...
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Article
Open AccessTranscription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia
Expression of the Sp1 transcription factor is induced by hypoxia, and the ADAM17 promoter contains predicted Sp1 binding sites. ADAM17 contributes to hypoxic-induce invasiveness of glioma. In this study, we in...
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Article
Open AccessIncreased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells
Heparanase is an endoglycosidase that degrades heparan sulfate, the main polysaccharide constituent of the extracellular matrix (ECM) and basement membrane. Expression of the heparanase gene is associated with...
