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Open AccessAberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers
ADAMs (a disintegrin and metalloproteinase) have long been associated with tumor progression. Recent findings indicate that members of the closely related ADAMTS (ADAMs with thrombospondin motifs) family are a...
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Article
Open AccessPhosphatidylserine exposure is required for ADAM17 sheddase function
ADAM17, a prominent member of the ‘Disintegrin and Metalloproteinase’ (ADAM) family, controls vital cellular functions through cleavage of transmembrane substrates. Here we present evidence that surface exposu...