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  1. Article

    Open Access

    The impact of ACE2 polymorphisms (rs1978124, rs2285666, and rs2074192) and ACE1 rs1799752 in the mortality rate of COVID-19 in different SARS-CoV-2 variants

    Clinical severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outcomes could be influenced by genetic polymorphisms in angiotensin I-converting enzyme (ACE1) and ACE2. This study aims to exami...

    Farzaneh Sheikhian, Sahar Sadeghi Mofrad, Samira Tarashi… in Human Genomics (2023)

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  2. Article

    Open Access

    Increased risk of COVID-19 mortality rate in IFITM3 rs6598045 G allele carriers infected by SARS-CoV-2 delta variant

    The interferon-induced transmembrane-protein 3 (IFITM3) is a vital component of the immune system's defense against viral infection. Variants in the IFITM3 gene have been linked to changes in expression and the r...

    Melika Gholami, Fatemeh Sakhaee, Fattah Sotoodehnejadnematalahi… in Human Genomics (2022)

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  3. Article

    Open Access

    On the relationship between tripartite motif-containing 22 single-nucleotide polymorphisms and COVID-19 infection severity

    The tripartite motif containing (TRIM)-22 participates in innate immune responses and exhibits antiviral activities. The present study aimed to assess of the relationship between TRIM22 single-nucleotide polymorp...

    Nidhal Raheem Juhi Al-Kaabi, Sepideh Chodari Khameneh… in Human Genomics (2022)

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