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  1. No Access

    Chapter

    Fabrication Technology of Chitosan-Based IPN: Drug Delivery Application

    Chitosan as a biocompatible and biodegradable polymer is a good candidate for preparation of interpenetrating polymer network (IPN) hydrogel with amino and hydroxyl groups. Chitosan-based IPNs can release thei...

    Ali Rastegari, Fatemeh Mottaghitalab… in Interpenetrating Polymer Network: Biomedic… (2020)

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    Article

    Inhibiting hepatic gluconeogenesis by chitosan lactate nanoparticles containing CRTC2 siRNA targeted by poly(ethylene glycol)-glycyrrhetinic acid

    Diabetes mellitus is a chronic metabolic disorder characterized by insulin deficiency and impaired glucose metabolism. Overexpression of cAMP response element binding protein (CREB)-regulated transcriptional c...

    Ali Rastegari, Fatemeh Mottaghitalab… in Drug Delivery and Translational Research (2019)

  3. No Access

    Article

    Corneal chemical burn treatment through a delivery system consisting of TGF-β1 siRNA: in vitro and in vivo

    Chemical burns are major causes of corneal blindness. Transforming growth factor beta-1 (TGFβ1) plays an important role in induction of corneal inflammation-related-fibrosis leading to the blindness. Here, a topi...

    Forouhe Zahir-Jouzdani, Masoud Soleimani… in Drug Delivery and Translational Research (2018)

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    Article

    Inhibiting influenza virus replication and inducing protection against lethal influenza virus challenge through chitosan nanoparticles loaded by siRNA

    Influenza virus causes a highly contagious viral respiratory tract infection with potentially fatal outcomes in humans and animals. There is now widespread influenza virus resistance to commercial drugs due to...

    Abbas Jamali, Fatemeh Mottaghitalab… in Drug Delivery and Translational Research (2018)