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Article
Open AccessPrevalence of supplement usage and related attitudes and reasons among fitness athletes in the gyms of Kashan and its relationship with feeding behavior: a cross-sectional study
The overuse of supplements among athletes is a widespread issue affecting the health of both male and female athletes. However, research on supplements usage among female fitness athletes is limited, and there...
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Article
Rosuvastatin attenuates total-tau serum levels and increases expression of miR-124-3p in dyslipidemic Alzheimer's patients: a historic cohort study
microRNAs are candidate diagnostic biomarkers for Alzheimer's disease. This study aimed to compare Silymarin with Rosuvastatin and placebo on total-Tau protein level and expression levels of microRNAs and TGF-...
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Article
Arthrospira platensis and Gracilaria gracilis algae extracts as biological inducers for human amniotic mesenchymal stem cells (hAMSC)
The use of mesenchymal stem cells is a promising strategy for treating bone-related diseases. Therefore, the development of agents capable of inducing the differentiation of stem cells into osteoblasts is bene...
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Article
In Silico Interactions of Natural and Synthetic Compounds with Key Proteins Involved in Alzheimer’s Disease: Prospects for Designing New Therapeutics Compound
Memory impairment is a result of multiple factors including amyloid-beta (Aβ) accumulation. Several receptors are mediated for Aβ transport and signaling. Moreover, blood lipids are involved in Aβ signaling pa...
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Article
Correction: Autophagic Molecular Alterations in the Mouse Cerebellum Experimental Autoimmune Encephalomyelitis Model Following Treatment with Cannabidiol and Fluoxetine
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Article
Autophagic Molecular Alterations in the Mouse Cerebellum Experimental Autoimmune Encephalomyelitis Model Following Treatment with Cannabidiol and Fluoxetine
The crosstalk between autophagy and apoptosis is one of the most important processes involved in the cell program death, and several mechanisms including oligodendrocyte apoptosis and autophagy play significan...
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Article
Open AccessEffect of soy isoflavones supplementation on migraine characteristics, mental status and calcitonin gene-related peptide (CGRP) levels in women with migraine: results of randomised controlled trial
Literature suggests a relationship between estrogen levels and migraine headache pathogenesis. However, the effect of soy isoflavones on migraine characteristic remains unclear. This study aimed to investigate...
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Article
Quantifying and qualifying hospital pharmaceutical waste: a case study in Tehran, Iran
Nowadays, hospital waste management is particularly important due to its potential pathogenicity and serious hazards and is considered as one of the most important environmental problems. One of the prominent ...
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Article
Targeting neuroinflammation by intranasal delivery of nanoparticles in neurological diseases: a comprehensive review
Neuroinflammation (NIF) plays an essential role in the pathology of neurological disorders like Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, and epilepsy. Despite progress in the drug discover...
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Article
miR-219 overexpressing oligodendrocyte progenitor cells for treating compression spinal cord injury
Oligodendrocyte progenitor cells (OPCs) transplantation has been considered a promising treatment for spinal cord injury, according to previous studies. Recent research shed light on the importance of microRNA...
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Article
Olfactory mucosa stem cells delivery via nasal route: a simple way for the treatment of Parkinson disease
Finding a simple and effective way for transferring cells to the brain lesion site with minimum side effects mounts a challenge in cell therapy. Cell delivery via nasal route using the bypassing the blood-brai...
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Article
Open AccessEffect of omega-3 fatty acids supplementation on cardio-metabolic and oxidative stress parameters in patients with chronic kidney disease: a systematic review and meta-analysis
Omega-3 fatty acids (FAs) have been suggested as a beneficial supplement in chronic kidney disease (CKD) patients, but the results of randomized clinical trials (RCTs) are controversial. We conducted a systematic...
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Article
Cascade process for direct synthesis of indeno[1,2-b]furans and indeno[1,2-b]pyrroles from diketene and ninhydrin
Novel and efficient multicomponent reactions (MCRs) involving diketene, ninhydrin (indane-1,2,3-trione) and one primary amine (3CR) or two different primary amines (4CR) were achieved for the successful synthe...
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Article
The expressions of NLRP1, NLRP3, and AIM2 inflammasome complexes in the contusive spinal cord injury rat model and their responses to hormonal therapy
Spinal cord injury (SCI) is a devastating condition with a growing incidence in develo** countries. The activity of inflammasome complexes initiates neuroinflammation, which is a key player in SCI pathogenes...
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Article
Beta-Amyloid-Dependent miRNAs as Circulating Biomarkers in Alzheimer’s Disease: a Preliminary Report
MicroRNAs (miRNAs) are considered among the most reliable biomarkers to diagnose and predict Alzheimer’s disease (AD), due to their regulatory nature. The main goal of this study was to evaluate the expression...
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Article
Comparative phenotypic characterization of human colostrum and breast milk-derived stem cells
There is a diverse population of stem cells in human breast milk that can be employed for therapeutic purposes as a reservoir of cells. The current study mainly aimed to determine the nature markers expressing...
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Article
Alpha-lipoic acid mitigates toxic-induced demyelination in the corpus callosum by lessening of oxidative stress and stimulation of polydendrocytes proliferation
Multiple Sclerosis (MS), is a disease that degenerates myelin in central nervous system (CNS). Reactive oxygen species (ROSs) are toxic metabolites, and accumulating data indicate that ROSs-mediated apoptosis ...
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Chapter and Conference Paper
Creating a Sense of Unity: From Quantified Self to Qualitative Space
The design and usage of Personal Informatics (PI) systems have been subjects of rapidly growing interest in recent years. PI systems are typically designed to monitor individuals’ physical activity and encoura...
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Chapter
Getting It Going: Explorations at the Intersection of Moving Bodies, Information Technology and Architecture
Our bodily experience of space and time is primarily con by the architecture around us. Through architecture we fuse our image of self with our experience in the world. It articulates our experience of being-i...
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Article
Gemfibrozil Pretreatment Resulted in a Sexually Dimorphic Outcome in the Rat Models of Global Cerebral Ischemia–Reperfusion via Modulation of Mitochondrial Pro-survival and Apoptotic Cell Death Factors as well as MAPKs
Inducers of mitochondrial biogenesis are widely under investigation for use in a novel therapeutic approach in neurodegenerative disorders. The ability of Gemfibrozil, a fibrate, is investigated for the first ...
