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Article
Iranian patients with diabetes and COVID-19-associated mucormycosis: Characteristics, manifestations, and mortality risk factors
This study evaluated the mortality risk factors in Iranian patients with diabetes mellitus (DM) and COVID-19-associated mucormycosis (CAM).
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Article
Mixed Aspergillosis and Mucormycosis Infections in Patients with COVID-19: Case Series and Literature Review
Mucormycosis and aspergillosis are angioinvasive infections mainly occurring in immunocompromised patients. However, mixed infection with mucormycosis and aspergillosis in post-COVID-19 patients is rare. In th...
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Article
COVID-19 Associated Rhino-Orbital-Cerebral Mucormycosis: Clinical Features, Antifungal Susceptibility, Management and Outcome in a Tertiary Hospital in Iran
Despite the unprecedented surge in the incidence of mucormycosis in the COVID-19 era, the antifungal susceptibility patterns (ASPs) of COVID-19 associated mucormycosis (CAM) isolates have not been investigated...
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Article
Effect of PEG Molecular Weight and Volume Ratio of Chitosan/PEG and Silk Fibroin on Physicomechanical Properties of Chitosan/PEG-SF Scaffold as a Bio-mimetic Substrate in Skin-tissue Engineering Applications
Tissue engineering provides new approaches to improve skin lesions. However, cell differentiation onto the engineered substrate with the skin-like pattern is the main challenge. Here we have tried to fabricate...
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Article
Interference with zinc homeostasis and oxidative stress induction as probable mechanisms for cadmium-induced embryo-toxicity in zebrafish
The present study was conducted to provide new insights into the mechanisms that may be responsible for cadmium (Cd)-induced toxicity in zebrafish larvae as well as the role of the trace element zinc (Zn) in r...
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Article
Open AccessDrug-induced ectropion following the chronic use of topical Natamycin
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Article
Shifting to very early endoscopic DCR in acute suppurative dacryocystitis
We aimed to show the outcome of very early endoscopic dacryocystorhinostomy (VE-EDCR) in a routine pool of patients with acute dacryocystitis (AD) and abscess formation compared with the standard late external...
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Article
Open AccessExtracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury
Retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress this neurodegeneration. Various somati...
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Article
Traumatic optic neuropathy treatment trial (TONTT): open label, phase 3, multicenter, semi-experimental trial
Intravenously administered erythropoietin (EPO) was firstly commenced (phase 1) in patients with indirect traumatic optic neuropathy (TON) by this group in 2011. It was re-tested by another group (phase 2) in ...
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Article
Open AccessGlyceollins trigger anti-proliferative effects through estradiol-dependent and independent pathways in breast cancer cells
Estrogen receptors (ER) α and β are found in both women and men in many tissues, where they have different functions, including having roles in cell proliferation and differentiation of the reproductive tract....
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Article
Open AccessCOUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration
The orphan receptors COUP-TF (chicken ovalbumin upstream promoter transcription factor) I and II are members of the nuclear receptor superfamily that play distinct and critical roles in vertebrate organogenesi...
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Article
Long-term follow-up of invasive ocular surface squamous cell carcinoma treated with excision, cryotherapy, and topical mitomycin C
To evaluate the efficacy of surgical excision, cryotherapy and topical Mitomycin C (MMC) for ocular surface squamous cell carcinoma (SCC) with at least 24 months follow-up.
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Article
Epigenetic memories: structural marks or active circuits?
A hallmark of living systems is the management and the storage of information through genetic and epigenetic mechanisms. Although the notion of epigenetics was originally given to any regulation beyond DNA seq...
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Article
Erythropoietin: a novel treatment for traumatic optic neuropathy—a pilot study
To determine the visual outcome and safety of intravenous erythropoietin in patients with indirect traumatic optic neuropathy (TON).
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Article
COUP-TFI modulates estrogen signaling and influences proliferation, survival and migration of breast cancer cells
We previously showed that COUP-TFI interacts with the Estrogen Receptor alpha (ERα) to recruit Extracellular signal Regulated Kinases (ERKs) in an Estradiol (E2)-independent manner, resulting in an enhancement...
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Article
Estrogen receptors: Ligand discrimination and antiestrogen action
We have used affinity labeling, site-directed mutagenesis and regional chemical mutagenesis in order to determine regions of the estrogen receptor (ER) important in hormone binding, ligand discrimination betwe...
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Article
cDNA and amino acid sequences of rainbow trout (Oncorhynchus mykiss) lysozymes and their implications for the evolution of lysozyme and lactalbumin
The complete 129-amino-acid sequences of two rainbow trout lysozymes (I and II) isolated from kidney were established using protein chemistry microtechniques. The two sequences differ only at position 86, I ha...
