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Protocol
Prenatal Diagnosis of Chromosomal Abnormalities Using Maternal Blood
Fetal chromosomal aneuploidies can be detected by fluorescent in situ hybridization (FISH) analysis of intact fetal cells circulating in maternal blood. Given the low number of circulating fetal cells (1 in 104 t...
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Article
Genomic instability due to germline p53 mutations drives preneoplastic Progression toward cancer in human cells
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Article
The current state of oncogenes and cancer: Experimental approaches for analyzing oncogenetic events in human cancer
The development of cancer is a multistage process. The activation of proto-oncogenes and the inactivation of tumor suppressor genes play a critical role in the induction of tumors. Using human cell model syste...